China Factory Direct
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| CAS number | 134418-28-3 |
| Product name | Dehydroandrographolide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Development of anti-inflammatory and antiviral drugs | Used as an active pharmaceutical ingredient in the synthesis of anti-inflammatory and antiviral drug formulations |
| Pharmaceuticals | Anticancer research | Applied in structural modification and structure–activity relationship (SAR) studies of anticancer agents |
| Natural Products Chemistry | Intermediate synthesis | Applied in structural optimization and derivatization reactions of andrographolide-type compounds |
| Biotechnology | Pharmacological research | Used as an experimental reagent for biological activity evaluation in cellular or animal models |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies dehydrated andrographolide by UV absorption at 225 nm using a reversed-phase C18 column and external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., andrographolide, neoandrographolide) via gradient elution and peak area comparison. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) using flame ionization detection with headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (Pb, Cd, As, Hg) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic residue after high-temperature ashing (700-800 C) and subsequent weighing. |
| Specific Optical Rotation | Polarimetry | Measures optical activity using sodium D-line light to confirm chiral integrity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry powder form using Mie scattering theory. |
| Microbial Enumeration | Membrane Filtration | Quantifies aerobic mesophilic bacteria and fungi via filtration, membrane transfer, and colony counting on selective media. |
| Endotoxin Level | Kinetic Chromogenic LAL Assay | Detects bacterial endotoxins by measuring color development from Limulus amebocyte lysate enzymatic cascade. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 228-232°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -75° to -85° (c=1, in methanol) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.