4-Bromo-2-fluoro-5-nitrotoluene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1345471-69-3 |
| Product name | 4-Bromo-2-fluoro-5-nitrotoluene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromo-2-fluoro-5-nitrotoluene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromo-2-fluoro-5-nitrotoluene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromo-2-fluoro-5-nitrotoluene
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of anticancer agents or kinase inhibitors | Constructs the active molecular scaffold via nucleophilic substitution, reduction, or coupling reactions |
| Agrochemicals | Used to synthesize fluorinated aromatic agrochemical compounds | Prepares the target agrochemical molecule via Suzuki coupling, nitro group reduction, and related steps |
| Organic Synthesis | Multifunctional substituted aromatic building block | Enables metalation (e.g., lithiation, magnesiation) or palladium-catalyzed cross-coupling reactions via the bromine atom; the nitro group is reduced to an amino group for subsequent functional group transformations |
Manufacturing Quality Control of 4-Bromo-2-fluoro-5-nitrotoluene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., isomers, dehalogenated or reduced by-products) using gradient HPLC-UV with relative response factors. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., toluene, DMF, methanol) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| Bulk Density | Tap Density Tester | Measures mass per unit volume after standardized tapping (ASTM D1895) to assess powder flow and handling characteristics. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using Mie scattering theory and optical detection. |
| Organic Volatile Impurities (OVI) | GC-MS | Identifies and quantifies unknown volatile organic impurities using gas chromatography coupled with mass spectrometric detection. |
Technical Specifications of 4-Bromo-2-fluoro-5-nitrotoluene
| Test Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Purity | >=98.5% |
| Melting Point | 78–82°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromo-2-fluoro-5-nitrotoluene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromo-2-fluoro-5-nitrotoluene
Safety Information of 4-Bromo-2-fluoro-5-nitrotoluene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Bromo-2-fluoro-5-nitrotoluene
Industrial 4-Bromo-2-fluoro-5-nitrotoluene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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