3-Bromo-2-hydroxypyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13466-43-8 |
| Product name | 3-Bromo-2-hydroxypyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Bromo-2-hydroxypyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Bromo-2-hydroxypyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Bromo-2-hydroxypyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of anticancer agents, kinase inhibitors, and other active pharmaceutical ingredients | Used as a key structural unit in coupling reactions (e.g., Suzuki, Heck) or nucleophilic substitution reactions to construct pyridine-containing pharmacophores |
| Agrochemical R&D | Structural modification and lead compound optimization for novel insecticides and fungicides | Functionalized via bromine atom transformation to introduce thioether, amino, or aryl groups, enhancing biological activity and selectivity |
| Organic Synthesis | Heterocycle functionalization reagent and ligand precursor | Applied to prepare di-functionalized pyridine derivatives bearing both hydroxyl and halogen groups, which are further converted into metal-complex ligands (e.g., N,O-donor ligands for Pd- or Cu-catalyzed systems) |
Manufacturing Quality Control of 3-Bromo-2-hydroxypyridine
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities under natural or standard lighting conditions. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol/water or acetonitrile/water (with buffer salt) as the mobile phase. Detection is performed using a UV detector, and purity is calculated by external standard or normalization method. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Uses ¹H-NMR and ¹³C-NMR to identify the chemical environment of hydrogen and carbon atoms, confirming consistency with the target structure. |
| Structure Confirmation | Mass Spectrometry (MS) | Determines the molecular ion peak using ESI or EI ionization to confirm molecular weight; fragment ion peaks are analyzed to further verify the structure. |
| Melting Point | Melting Point Determination (Capillary Method) | Fill the sample into a capillary tube and gradually heat it in a melting point apparatus. Record the initial and final melting temperatures to determine if the melting range meets the standard. |
| Water Content | Karl Fischer Titration (KF) | Measures the water content using a KF titrator, suitable for trace moisture analysis, with accurate and reliable results. |
| Residual Solvents | Gas Chromatography (GC) | Detects organic solvents possibly remaining from the manufacturing process (e.g., methanol, ethanol, dichloromethane) according to ICH guidelines, using an FID detector. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determines the content of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeia or safety standards. |
| Residue on Ignition | Residue on Ignition Test | Ignite the sample at high temperature until constant weight, then weigh the residue to assess the level of inorganic impurities. |
| Individual and Total Impurities | HPLC Method | Analyzes impurity peak areas from the HPLC chromatogram to calculate the content of individual and total impurities, typically using area normalization or external standard method. |
Technical Specifications of 3-Bromo-2-hydroxypyridine
| Test Item | Specification |
|---|---|
| Appearance | White to gray to red crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 75-79°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Bromo-2-hydroxypyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Bromo-2-hydroxypyridine
Packaging of 3-Bromo-2-hydroxypyridine
Industrial 3-Bromo-2-hydroxypyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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