3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 134672-70-1 |
| Product name | 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for the antifungal drug voriconazole | (S)-3-(2,4-Difluorophenyl)propionic acid is synthesized via asymmetric hydrogenation or chiral resolution, followed by multiple steps—including acid chloride formation, aminolysis, and cyclization—to construct the triazole side chain of voriconazole |
Manufacturing Quality Control of 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification based on relative retention times and response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated external standards. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic detection for high sensitivity and specificity. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified via calibration curve using sodium chloride standard. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the solid converts to liquid; correlates with crystalline purity and identity. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution; used to confirm chiral integrity and enantiomeric excess. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile inorganic residue after high-temperature ashing (700-800 C) of sample; indicates inorganic impurity load. |
| pH of Aqueous Suspension | pH Meter | Electrochemical measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water), indicating acidic/basic impurities or degradation. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. scattering angle to derive volume-based particle size distribution in dry or wet dispersion. |
| Microbial Limits | Membrane Filtration and Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) using selective agar media and incubation. |
Technical Specifications of 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID
Safety Information of 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID
Industrial 3-(2,4-DIFLUOROPHENYL)PROPIONIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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