China Factory Direct
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| CAS number | 13485-59-1 |
| Product name | L-Alanyl-L-proline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Used as a drug intermediate or active pharmaceutical ingredient (API) in research on antihypertensive, anti-inflammatory, and neuroprotective effects | Purification following peptide synthesis, solid-phase peptide synthesis (SPPS), or solution-phase synthesis |
| Biochemical Research | Employed as a dipeptide model compound to study peptide bond stability, enzymatic degradation behavior, and transport mechanisms | Enzymatic reactions, mass spectrometry analysis, and cell culture experiments |
| Cosmetics | Applied as a skin-conditioning agent or anti-aging ingredient to promote collagen synthesis | Incorporated into emulsions, serums, and other formulations for transdermal delivery |
| Food Science (Research Stage) | Investigated for potential use as a functional food ingredient, e.g., to support gut health or provide antioxidant activity | Micronization, microencapsulation, or co-formulation with other amino acids or peptides |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~200–210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., dipeptide isomers, hydrolysis products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection (or mass spectrometry) to quantify volatile organic solvents (e.g., methanol, ethyl acetate, DMF) per ICH Q3C. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of toxic elements (e.g., Pb, Cd, As, Hg) after acid digestion, using inductively coupled plasma mass spectrometry or optical emission spectroscopy. |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation using a polarimeter at 589 nm (Na-D line) to confirm stereochemical integrity and enantiomeric purity. |
| pH (1% w/v aqueous solution) | pH Meter | Measurement of hydrogen ion activity in a standardized aqueous solution using calibrated pH electrode, reflecting acid-base behavior of the zwitterionic dipeptide. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Ignition at 600–750 °C followed by gravimetric determination of non-volatile inorganic residue, indicating inorganic ash content. |
| Microbial Limits | Membrane Filtration + TSA/SDA Culture | Enumeration of aerobic mesophilic bacteria and fungi via filtration, membrane transfer to tryptic soy agar and sabouraud dextrose agar, followed by incubation and colony counting. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed powder using laser scattering to determine volumetric particle size distribution (e.g., D10, D50, D90). |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–220 °C |
| Optical Rotation | -15.0 to -19.0 ° (c=1, H2O) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.