N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 135042-17-0 |
| Product name | N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of antiviral drug intermediates | Used as a chiral building block to construct peptide-based drug molecules |
| Pharmaceutical R&D | Preparation of protease inhibitors | Introduced into the target molecular scaffold via deprotection and coupling reactions |
| Biochemistry | Peptide synthesis modifier | Applied in hydroxyl protection strategies for solid-phase or solution-phase peptide synthesis |
| Organic Synthesis | Chiral auxiliary or catalyst precursor | Employed in asymmetric synthesis reactions to control stereoselectivity |
| Chemical Reagents | Compound for laboratory research | Used in studies optimizing Boc protecting group stability and hydrolysis conditions |
Manufacturing Quality Control of N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase with UV detection; calculation of enantiomeric excess from peak areas. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Quantitative determination of trace metal impurities (e.g., Pb, Cd, Ni) by mass spectrometric detection after acid digestion. |
| Residual Palladium | ICP-OES | Determination of palladium content following microwave-assisted acid digestion and plasma optical emission spectroscopy. |
| Related Substances | HPLC-UV | Identification and quantification of structurally related impurities using gradient reversed-phase HPLC with UV detection. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at specified temperature and wavelength (typically 589 nm and 20 C). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as the temperature range over which solid-to-liquid phase change occurs under controlled heating. |
| Residual Chloride | Ion Chromatography | Quantification of chloride ions via suppressed conductivity detection after anion exchange separation. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate particle size distribution in a dispersed dry or wet sample. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens using standardized culture-based methods. |
Technical Specifications of N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Optical Rotation | +77.0 to +79.0° (c=1, in methanol) |
| Melting Point | 128.0 to 132.0°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
Safety Information of N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
Industrial N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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