China Factory Direct
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| CAS number | 13505-32-3 |
| Product name | N-(P-TOLUENESULFONYL)-L-PHENYLALANINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for preparing angiotensin-converting enzyme (ACE) inhibitors (e.g., enalapril) | Key building block in chiral resolution or asymmetric synthesis |
| Biochemistry | Specific inhibitor of proteases (e.g., chymotrypsin) for enzymatic mechanism studies | Binds to the enzyme active site to inhibit catalytic activity |
| Research Reagents | Reference standard for method development and validation in analytical chemistry (e.g., HPLC, mass spectrometry) | Qualitative/quantitative standard in chromatographic separation or spectroscopic analysis |
| Organic Synthesis | Building block for synthesizing complex molecules containing phenylalanine structural units, such as peptide derivatives or functionalized amino acids | Protected amino acid derivative participating in condensation reactions or functional group transformations |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe sample color, physical form (e.g., white or off-white crystalline powder), and check for foreign matter, moisture absorption, or caking. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (e.g., 220 nm or 254 nm); quantify main component purity by peak area normalization or external standard method. |
| Related Substances | HPLC (Gradient Elution) | Employ gradient elution to separate impurities; compare with reference standards of known impurities or use relative retention times to quantify individual impurity levels. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range according to pharmacopoeial methods to assess crystallinity and purity (typical value approximately 130–135°C). |
| Specific Optical Rotation | Polarimetry | Measure optical rotation at a specified wavelength (usually sodium D line, 589 nm) and concentration to confirm chiral configuration (L-configuration). |
| Loss on Drying | Weight Loss upon Drying (105°C to Constant Weight) | Weigh sample in a pre-weighed, constant-weight weighing bottle; dry at 105°C until constant weight is achieved, then calculate percentage weight loss to evaluate moisture and volatile content. |
| Sulfated Ash | High-Temperature Ashing in Muffle Furnace | Char the sample and then incinerate at 600–800°C; weigh the residual inorganic material to estimate total inorganic salts or metal impurities. |
| Heavy Metals | Thioacetamide Method or ICP-MS | Perform limit test using thioacetamide colorimetric method per Chinese Pharmacopoeia, or use ICP-MS for precise determination of elemental contents such as lead, arsenic, cadmium, and mercury. |
| pH Value | pH Meter Measurement (in aqueous solution or buffer) | Prepare a solution of defined concentration in water, measure pH using a calibrated pH meter to assess acidity or basicity (typically slightly acidic). |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | According to ICH Q3C guidelines, analyze residual organic solvents (e.g., methanol, ethanol, ethyl acetate) using capillary GC-FID or GC-MS. |
| Structural Confirmation | Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR) | IR: Compare characteristic functional group absorption peaks; NMR: Use ¹H/¹³C NMR to confirm molecular structure, substitution patterns, and stereochemistry. |
| Assay | HPLC External Standard Method or Non-aqueous Titration | HPLC external standard method: Quantify using a calibration curve established with reference standard; non-aqueous titration: Titrate amino groups with perchloric acid in glacial acetic acid medium. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -3.0 to -2.0° (c=1, in DMF) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.