(R)-N-Boc-2-(hydroxymethyl)morpholine is supplied directly from the manufacturing plant in bulk industrial quantities and is widely utilized in the synthesis of agrochemical active ingredients, the preparation of specialty chemicals in fine chemical manufacturing, and the construction of functional molecules for materials science applications.

Catalog

(R)-N-Boc-2-Hydroxymethylmorpholine Bulk Supply for Industrial Use

China Factory Direct
	CAS number	135065-71-3
	Product name	(R)-N-Boc-2-Hydroxymethylmorpholine
	Stock	Stock readily available; annual supply capacity exceeding 1,000 tons.
	Grade	Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade
	Packaging	25KG/bag500KG/bag1000KG/bag
	Sample	Test Samples Available (Click to Request Samples)
	COA	View COA
	Price	Get Quote
	Supply Type	Bulk / Contract manufacturing / OEM
	Shipping	FCL / LCL available
	Payment Terms	Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
	Manufacturer	Greenrock Chemical(China Factory)

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CAS No:135065-71-3

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Documents We Provide for (R)-N-Boc-2-Hydroxymethylmorpholine

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart

Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.

Bulk (R)-N-Boc-2-Hydroxymethylmorpholine Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of (R)-N-Boc-2-Hydroxymethylmorpholine

Industry	Application	Process
Pharmaceuticals	Chiral intermediates	Used in asymmetric synthesis and protecting group chemistry
Agrochemicals	Synthesis of active pharmaceutical ingredients (APIs)	Used in functional group transformations and coupling reactions
Fine chemicals	Synthesis of specialty chemicals	Used in catalytic hydrogenation and substitution reactions
Materials science	Construction of functional molecules	Used in polymer modification and crosslinking reactions

Manufacturing Quality Control of (R)-N-Boc-2-Hydroxymethylmorpholine

Detection Item	Common Analytical Method	Method Overview
Assay (Purity)	HPLC-UV	Quantifies main component using reversed-phase HPLC with UV detection at 210-220 nm, comparing peak area to a certified reference standard.
Enantiomeric Purity	Chiral HPLC	Resolves (R)- and (S)-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio.
Residual Solvents	GC-FID	Separates and quantifies volatile organic solvents (e.g., THF, EtOAc, MeOH) using gas chromatography with flame ionization detection.
Water Content	Karl Fischer Titration	Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol medium.
Heavy Metals	ICP-MS	Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion by measuring isotopic mass-to-charge ratios.
Residual Chloride	Ion Chromatography	Separates and detects chloride ions using suppressed conductivity detection after aqueous extraction.
Residual Palladium	ICP-OES	Measures palladium content post-microwave digestion by monitoring characteristic atomic emission lines.
Appearance	Visual Inspection	Assesses physical state, color, and presence of visible particulates or foreign matter under controlled white light against standard references.
Melting Point	Capillary Melting Point Apparatus	Determines temperature range of solid-to-liquid transition using calibrated capillary method per USP <741>.
Specific Optical Rotation	Polarimetry	Measures angle of rotation of plane-polarized light in solution to confirm chiral integrity and concentration.
Related Substances	HPLC-UV	Detects and quantifies structurally related impurities (e.g., de-Boc, N-oxide, diastereomers) using gradient reversed-phase HPLC.
Residue on Ignition	Gravimetric Analysis	Determines inorganic ash content by high-temperature incineration followed by precise weighing of residual residue.

Technical Specifications of (R)-N-Boc-2-Hydroxymethylmorpholine

Test Item	Specification
Appearance	Pale-yellow solid
Purity	>=98.0% (GC-MS)
Optical Rotation	-22.0 to -19.0 deg (c=1, in CHCl3)
Water Content (KF)	<=0.5%
Total Impurities	<=2.0%
Single Impurity	<=0.5%
Melting Point	65.0 to 69.0 °C
Identification (NMR)	Consistent with structure
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of (R)-N-Boc-2-Hydroxymethylmorpholine

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NMR Spectra of (R)-N-Boc-2-Hydroxymethylmorpholine

Safety Information of (R)-N-Boc-2-Hydroxymethylmorpholine

Pictograms
Signal Word	Warning
Safety Data Sheet

Packaging of (R)-N-Boc-2-Hydroxymethylmorpholine

We have a diverse range of chemicals in stock. Available in Bagged goods (25 kg.),Big bags (500 kg.), Big bags (1000 kg.).

Industrial (R)-N-Boc-2-Hydroxymethylmorpholine Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

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