(S)-N-Boc-2-Hydroxymethylmorpholine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 135065-76-8 |
| Product name | (S)-N-Boc-2-Hydroxymethylmorpholine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for (S)-N-Boc-2-Hydroxymethylmorpholine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-N-Boc-2-Hydroxymethylmorpholine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-N-Boc-2-Hydroxymethylmorpholine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in drug synthesis | Converted to an ester via reaction with a specific acid, followed by multiple chemical transformations to construct complex molecular architectures |
| Chemical Research | Employed as a protecting group in organic synthesis | The amino group of the target compound is first protected using N-tert-butoxycarbonyl-(S)-2-morpholinomethanol; the protecting group is subsequently removed selectively as required |
| Drug Development | Preparation of biologically active chiral compounds | A chiral center is introduced via asymmetric catalysis or other methods, followed by downstream processing—such as deprotection—to yield the final product |
Manufacturing Quality Control of (S)-N-Boc-2-Hydroxymethylmorpholine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase and UV detection, resolving (S)-enantiomer from potential (R)-impurity. |
| Residual Solvents | GC-FID | Identification and quantification of common solvents (e.g., THF, ethyl acetate, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent to determine trace water content. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against sodium chloride standard. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 750 C followed by sulfuric acid treatment and final weighing to determine inorganic residue mass. |
| Optical Rotation | [alpha]D Measurement | Specific rotation measured at 589 nm (Na D-line) in solution using a digital polarimeter; verifies chiral integrity and concentration. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed via capillary method; confirms identity and crystallinity consistency. |
| Related Substances | HPLC-UV (Forced Degradation) | Detection and quantification of structurally related impurities (e.g., de-Boc, oxidation, hydrolysis products) under stressed conditions. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of Pd catalyst residue after microwave digestion, using isotope-dilution or external calibration. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determined in 1% w/v suspension in purified water using calibrated pH electrode; indicates acidic/basic impurity load. |
Technical Specifications of (S)-N-Boc-2-Hydroxymethylmorpholine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +18.5 to +19.5 deg (c=1, in methanol) |
| Melting Point | 72.0 to 76.0 °C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of (S)-N-Boc-2-Hydroxymethylmorpholine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-N-Boc-2-Hydroxymethylmorpholine
Safety Information of (S)-N-Boc-2-Hydroxymethylmorpholine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-N-Boc-2-Hydroxymethylmorpholine
Industrial (S)-N-Boc-2-Hydroxymethylmorpholine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply