China Factory Direct
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| CAS number | 135273-01-7 |
| Product name | (FMOC-CYS-OH)2 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Protecting group in peptide synthesis | Used as an Fmoc-protected cystine derivative in solid-phase or solution-phase peptide synthesis to prevent unwanted side reactions of amino groups during coupling |
| Chemical Synthesis | Synthesis of disulfide bond-containing peptides or protein fragments | Enables site-specific protection of cysteine residues and subsequent controlled disulfide bond formation in target peptide chains |
| Pharmaceutical R&D | Design and synthesis of drug molecules with defined structural and functional properties | Serves as a key intermediate in the construction of complex molecules, including targeted therapeutics and antibody–drug conjugates (ADCs) |
| Biotechnology | Protein engineering and structural studies | Applied to precisely control disulfide bond formation in proteins, supporting studies of protein folding and stability |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (FMOC-Cystine Content) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., FMOC-cysteine, dicyclohexylamine, oxidation products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Identification and quantification of solvents (e.g., DMF, dichloromethane, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration and weighing of the residual residue. |
| Optical Rotation | [a]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| pH of Solution | Potentiometric pH Measurement | Measurement of aqueous suspension or solution pH using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering to determine volume-based particle size distribution. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic microorganisms using membrane filtration followed by incubation on soybean-casein digest agar. |
| Endotoxins | Kinetic Chromogenic LAL Assay | Detection of bacterial endotoxins using Limulus amebocyte lysate reagent, measuring color development rate proportional to endotoxin concentration. |
| Residual Catalyst (Pd) | ICP-MS | Ultra-trace quantification of palladium from hydrogenation catalysts using inductively coupled plasma mass spectrometry after microwave digestion. |
| Test Item | Specification |
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| Appearance | White Solid |
| Purity | >=98.5% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Optical Rotation | -148±5° (c=1, in 1M HCl) |
| Melting Point | 220–225°C (decomposes) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.