China Factory Direct
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| CAS number | 13535-01-8 |
| Product name | 3-Amino-5-bromopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antitumor, antiviral, or neuroactive compounds | Applied in constructing complex molecular frameworks via nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of heterocyclic compounds with insecticidal or fungicidal activity | Applied in introducing functional groups via halogen–metal exchange or transition-metal-catalyzed cross-coupling |
| Materials Science | Used in the preparation of organic optoelectronic materials or ligand precursors | Applied in modifying the pyridine ring—via functional group transformations (e.g., diazotization, amidation)—to tune electronic properties |
| Research | Used as an organic synthetic building block for constructing nitrogen-containing heterocyclic libraries | Applied in multi-step syntheses leveraging orthogonal reactivity of the amino and bromo groups for selective derivatization |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or standard light sources to determine if it meets the specified physical characteristics. |
| Purity | HPLC (High-Performance Liquid Chromatography) | Use a reverse-phase column (e.g., C18) with a UV detector. Determine the main component content and impurity levels by retention time and peak area, assessing the purity of the compound. |
| Content Determination | HPLC External Standard Method or Titration | HPLC method: Use a standard substance to draw a standard curve and quantitatively determine the content of 5-bromo-3-aminopyridine in the sample; titration can be used for rough quantitative analysis, such as non-aqueous titration (suitable for basic amines). |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze hydrogen and carbon chemical shifts, coupling constants, etc., using 1H-NMR and 13C-NMR to confirm the molecular structure matches the target compound. |
| Structural Confirmation | Mass Spectrometry (MS) | Determine the molecular ion peak ([M+H]+) using EI-MS or ESI-MS to verify the molecular weight and assist in structural confirmation. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, ethanol, dichloromethane) from the production process according to ICH guidelines. Use headspace injection GC-FID for analysis. |
| Moisture | Karl Fischer Titration | Quantitatively determine the moisture content in the sample using Karl Fischer reagent, suitable for precise measurement of low moisture content. |
| Melting Point | Melting Point Determination | Determine the initial and final melting temperatures using an automatic or manual melting point apparatus, and compare them with literature values to assess purity and consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Dissolve the sample and measure the residual amounts of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical or industrial safety standards. |
| Individual Impurities and Total Impurities | HPLC Method | Detect individual impurity peaks using normalization method or impurity reference substance method, controlling the limits of individual impurities and total impurities. |
| Test Item | Specification |
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| Appearance | White to yellow crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.