China Factory Direct
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| CAS number | 135673-97-1 |
| Product name | FMOC-CHA-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Amino acid protecting group for peptide synthesis intermediates | Used as the fluorenylmethyloxycarbonyl (Fmoc) protected derivative of β-cyclohexylalanine in solid-phase or solution-phase peptide synthesis to construct peptide chains with defined sequences |
| Biotechnology | Critical intermediate in peptide drug development | Applied to amino acids via activation with reagents such as Fmoc-Cl or Fmoc-OSu, followed by nucleophilic substitution with the amino group under basic conditions |
| Chemical Synthesis | Synthesis of structurally and functionally tailored non-natural amino acids | Leveraged for its aromatic ring structure and side-chain properties to design peptide-based molecules with enhanced stability and biological activity |
| Fine Chemicals | Production of high-value pharmaceutical intermediates | Employed in multi-step syntheses involving controlled condensation and deprotection steps to construct target compounds |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 260 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification by retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, dichloromethane) via headspace GC with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in pyridine/methanol medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using sodium D-line light in a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies metal impurities (e.g., Pb, Cd, Ni) after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection and external calibration. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in suspension using Mie scattering theory and optical diffraction pattern analysis. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in 1% w/v aqueous suspension using calibrated glass electrode pH meter. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and absence of specified pathogens (e.g., E. coli) by filtration, membrane transfer, and incubation on selective media. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=99.0% (LC-MS) |
| Optical Rotation | -21° to -25° (c=1, in DMF) |
| Melting Point | 128°C to 132°C |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.