4-(Trifluoromethyl)nicotinonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13600-43-6 |
| Product name | 4-(Trifluoromethyl)nicotinonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(Trifluoromethyl)nicotinonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(Trifluoromethyl)nicotinonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(Trifluoromethyl)nicotinonitrile
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing novel insecticides (e.g., flupyradifurone) | Used to prepare the flupyradifurone active ingredient via multistep reactions including substitution and cyclization with aniline derivatives |
| Pharmaceuticals | Used to synthesize candidate drug molecules containing a trifluoromethylpyridine moiety, exhibiting potential antitumor and anti-inflammatory activity | Serves as a heterocyclic scaffold unit bearing a CF₃-pyridine core, participating in pharmaceutical chemical modifications such as Suzuki coupling and reductive amination |
| Materials Science | Structural unit for electron-transport materials in organic light-emitting diode (OLED) devices | After bromination or iodination, undergoes Ullmann or Buchwald-Hartwig coupling with aromatic amines or carbazole derivatives to introduce the strongly electron-withdrawing trifluoromethylpyridyl group for LUMO energy level tuning |
Manufacturing Quality Control of 4-(Trifluoromethyl)nicotinonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-254 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV against qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., acetone, methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in a pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Ni, Fe) after acid digestion by inductively coupled plasma mass spectrometry with isotopic detection. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column with carbonate/bicarbonate eluent. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled charring and sulfuric acid treatment followed by high-temperature incineration and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of neat sample against standard white background under controlled lighting. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension prepared per specified ratio and equilibrated at 25 C. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder size distribution using Mie scattering theory after dispersion in air via jet sieve or vibratory feed. |
| Specific Optical Rotation | Polarimetry | Measures angular rotation of plane-polarized light through a solution of known concentration and path length at specified wavelength and temperature. |
Technical Specifications of 4-(Trifluoromethyl)nicotinonitrile
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Refractive Index (n20/D) | 1.475–1.485 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(Trifluoromethyl)nicotinonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(Trifluoromethyl)nicotinonitrile
Safety Information of 4-(Trifluoromethyl)nicotinonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-(Trifluoromethyl)nicotinonitrile
Industrial 4-(Trifluoromethyl)nicotinonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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