China Factory Direct
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| CAS number | 136050-67-4 |
| Product name | FMOC-CYS(4-MBZL)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an amino-protecting group in peptide synthesis | In solid-phase peptide synthesis (SPPS), the amino group of cysteine is protected with N-(9-fluorenylmethoxycarbonyl) (Fmoc), while the thiol group is protected with S-(4-methylbenzyl) to prevent oxidation and side reactions, enabling stepwise coupling and subsequent deprotection |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 260-280 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., diastereomers, deprotection products, oxidation byproducts) using gradient HPLC with UV monitoring. |
| Chiral Purity | Chiral HPLC | Enantioselective separation on a chiral stationary phase to determine L-enantiomer excess and detect D-cysteine containing impurities. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., DMF, DCM, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (e.g., Pb, Cd, As, Hg) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing (500-600 C) and weighing. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at specified concentration, temperature, and sodium D-line wavelength to confirm chiral integrity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering to determine D10, D50, D90 values per USP <429>. |
| pH of Solution | Potentiometric pH Measurement | Electrochemical measurement of hydrogen ion activity in a defined aqueous or aqueous-organic solution using calibrated pH electrode. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using controlled heating and visual or automated endpoint detection. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148°C to 152°C |
| Optical Rotation | -20.0° to -24.0° (c=1, DMF) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.