China Factory Direct
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| CAS number | 13679-70-4 |
| Product name | 5-Methylthiophene-2-carboxaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of heterocyclic structures in drug molecules | Thienyl group introduced via nucleophilic substitution, followed by selective oxidation to yield the target product |
| Agrochemical Intermediates | Preparation of insecticidal and fungicidal active ingredients | Coupling reaction with haloalkanes under specific conditions to construct the key molecular scaffold |
| Dye Intermediates | Synthesis of organic dyes with specialized photophysical properties | Cyclization to form the thiophene ring, followed by formylation |
| Materials Science | Used as a precursor for functional materials, such as organic semiconductors | Specific functional groups introduced via multi-step synthesis to optimize material performance |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection and Physical Property Measurement | Observe the sample's color and state (typically a colorless to pale yellow liquid), and measure physical parameters such as melting point, boiling point, and refractive index, which should comply with pharmacopoeia or company specifications. |
| Purity (Main Component Content) | Gas Chromatography (GC) | Using a capillary column (e.g., DB-5 or HP-INNOWAX) with an FID detector, internal or external standard method is used for quantification. The peak area of 5-methyl-2-thiophene carboxaldehyde is separated and measured to calculate the content (usually ≥98%). |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | After GC separation, MS is used for structural identification of impurities. Possible by-products such as 5-methyl-2-thiophene methanol, dimers, and oxidation products are detected, and the levels of individual and total impurities are controlled. |
| Water Content | Karl Fischer Titration | Measuring trace water using the coulometric or volumetric method to ensure that the water content is below the specified limit (e.g., ≤0.5%), avoiding impact on stability and reactivity. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | The sample is digested and then analyzed for heavy metal residues such as lead, cadmium, mercury, and arsenic, complying with ICH Q3D or pharmacopoeia limits (e.g., ≤10 ppm). |
| Solvent Residues | Headspace Gas Chromatography (HS-GC) | Detecting residual organic solvents (such as methanol, ethanol, ethyl acetate, DMF) used in the production process, controlling their levels according to ICH Q3C standards. |
| UV-Vis Absorption Spectrum | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measuring absorbance at specific wavelengths (e.g., 270–290 nm) to rapidly assess purity and characteristic absorption, assisting in identification and quantification (requires calibration curve). |
| Infrared Spectral Identification | Fourier Transform Infrared Spectroscopy (FTIR) | Obtaining the infrared absorption spectrum of the sample and comparing it with the standard spectrum to confirm the presence of functional groups (such as C=O stretching vibration of aldehyde group ~1700 cm⁻¹, characteristic peaks of thiophene ring). |
| Chloride/Sulfate Impurities | Colorimetry or Ion Chromatography | Detecting inorganic anion impurities through precipitation turbidity or ion chromatography, ensuring compliance with impurity control requirements for organic synthetic raw materials (e.g., Cl⁻ ≤10 ppm). |
| Volatile Impurities/Residual Solvents | Gas Chromatography (GC) | Using a temperature-programmed GC method to separate and quantify low-boiling-point volatile impurities, ensuring compliance with process residue control standards. |
| Thermal Stability/Decomposition Temperature | Thermogravimetric Analysis (TGA) | Measuring mass loss during heating to evaluate thermal stability and determine whether there are easily decomposable components, providing reference for storage conditions. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.565–1.575 |
| Relative Density (20°C/25°C) | 1.14–1.16 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.