TOTU Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 136849-72-4 |
| Product name | TOTU |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for TOTU
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk TOTU Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of TOTU
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Protein synthesis | Used in solid-phase peptide synthesis |
| Life science research | Peptide modification | Applied in liquid-phase peptide synthesis |
| Pharmaceutical R&D | Drug development | Employed for peptide chain ligation |
| Diagnostics reagents | Diagnostic reagent preparation | Used to introduce specific amino acids |
| Enzymology | Enzyme active-site probes | Applied for site-specific labeling |
| Immunology | Antibody production support | Facilitates antigen-antibody complex formation |
Manufacturing Quality Control of TOTU
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies TOTU content by UV absorbance at 210-220 nm using a reversed-phase C18 column and calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., HATU, OBTU, dipeptide adducts) via gradient elution and peak area comparison. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, acetonitrile, dichloromethane) using flame ionization detection after headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine generated electrochemically in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) at sub-ppb levels after acid digestion and plasma ionization. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| pH of Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and optical observation. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by angular rotation of plane-polarized light in solution at specified concentration and wavelength (589 nm). |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration (600-750 C) followed by precise weighing of residue. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size via Mie scattering pattern analysis of dispersed aerosol under controlled airflow. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
Technical Specifications of TOTU
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15.0 to -19.0° (c=1, DMF) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of TOTU
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of TOTU
Packaging of TOTU
Industrial TOTU Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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