2-CHLORO-5-FLUORO-3-NITROPYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 136888-21-6 |
| Product name | 2-CHLORO-5-FLUORO-3-NITROPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-CHLORO-5-FLUORO-3-NITROPYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-CHLORO-5-FLUORO-3-NITROPYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-CHLORO-5-FLUORO-3-NITROPYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for novel insecticides, used in synthesizing neonicotinoid insecticides such as flupyradifurone | Undergoes nucleophilic substitution with phenolic compounds to form C–O bonds |
| Pharmaceuticals | Key structural motif in anticancer agents and kinase inhibitors | Participates in cross-coupling reactions, including Suzuki coupling and Buchwald–Hartwig amination |
| Materials Science | Building block for organic optoelectronic functional materials, used as a dopant in OLED emissive layers | Introduces conjugated side chains via halogen exchange or metal-catalyzed coupling |
Manufacturing Quality Control of 2-CHLORO-5-FLUORO-3-NITROPYRIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., starting materials, intermediates, isomers) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, dichloromethane) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| Loss on Drying | Gravimetric Analysis | Measurement of weight loss after drying under specified vacuum/temperature conditions to determine volatile content. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per EP 2.2.3. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using laser scattering principles and Mie theory-based calculation. |
Technical Specifications of 2-CHLORO-5-FLUORO-3-NITROPYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-CHLORO-5-FLUORO-3-NITROPYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-CHLORO-5-FLUORO-3-NITROPYRIDINE
Safety Information of 2-CHLORO-5-FLUORO-3-NITROPYRIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-CHLORO-5-FLUORO-3-NITROPYRIDINE
Industrial 2-CHLORO-5-FLUORO-3-NITROPYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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