4-Ethyl-5-fluoro-6-hydroxypyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 137234-87-8 |
| Product name | 4-Ethyl-5-fluoro-6-hydroxypyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Ethyl-5-fluoro-6-hydroxypyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Ethyl-5-fluoro-6-hydroxypyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Ethyl-5-fluoro-6-hydroxypyrimidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antiviral drugs (e.g., abacavir synthesis) | Used in organic synthesis and condensation reactions |
| Agrochemicals | Precursor to active ingredients in insecticides or fungicides | Applied in fluorination and pyrimidine ring modification |
| Fine Chemicals | Raw material for functional materials (e.g., liquid crystals or fluorescent molecules) | Employed in catalytic reactions and purification processes |
| Research | Pyrimidine-based template compound for structure–activity relationship studies | Utilized in laboratory-scale synthesis and characterization analysis |
Manufacturing Quality Control of 4-Ethyl-5-fluoro-6-hydroxypyrimidine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Utilizes a reverse-phase column (e.g., C18) with mobile phases such as methanol/water or acetonitrile/water, and a UV detector (typically at 254 nm). It effectively separates the main component from impurities and quantifies purity. This method is a standard for quality control in pharmaceuticals and intermediates. |
| Impurity Identification and Quantification | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines the separation capability of HPLC with the qualitative and quantitative advantages of mass spectrometry. It can accurately identify structural analogs and synthetic byproducts, suitable for detecting and confirming the structure of trace impurities (e.g., ≤0.1%). |
| Content Determination | Gas Chromatography (GC) | Suitable for volatile compounds or those that can be made volatile after derivatization. Sample is introduced via headspace injection or chemical derivatization (e.g., silylation), separated using a capillary column, and quantified using a flame ionization detector (FID). Applicable under specific conditions. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide key information about molecular structure, such as substituent positions, ring systems, and stereochemistry. Used to confirm the correctness of the target compound's structure and often serves as a standard reference method. |
| Molecular Weight and Molecular Formula Confirmation | Mass Spectrometry (MS) | Electron Ionization (EI-MS) or Electrospray Ionization (ESI-MS) provides accurate molecular ion peaks ([M+H]⁺ or [M]⁺). When combined with high-resolution mass spectrometry (HRMS), it enables precise determination of molecular formulas for verifying molecular weight. |
| Residual Solvent Detection | Gas Chromatography (GC-FID/MS) | Used to detect residual organic solvents (e.g., ethanol, acetone, dichloromethane) from synthesis processes. Samples are introduced via headspace injection or direct injection, and quantified according to pharmacopoeia standards (e.g., ICH Q3A/Q3B). |
| Melting Point Determination | Micro Melting Point Apparatus Method | Observes the temperature range during the melting process to assess compound purity and physical properties. Often used as an auxiliary testing method, comparing results with literature values to verify material consistency. |
| UV-Visible Spectra (UV-Vis) | UV-Vis Spectrophotometry | Measures absorption characteristics at specific wavelengths (e.g., 250–270 nm) for rapid qualitative identification of the target compound. Can also estimate solution concentration but is not suitable for precise quantification in complex mixtures. |
Technical Specifications of 4-Ethyl-5-fluoro-6-hydroxypyrimidine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 182–186 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Ethyl-5-fluoro-6-hydroxypyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Ethyl-5-fluoro-6-hydroxypyrimidine
Safety Information of 4-Ethyl-5-fluoro-6-hydroxypyrimidine
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Ethyl-5-fluoro-6-hydroxypyrimidine
Industrial 4-Ethyl-5-fluoro-6-hydroxypyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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