BOC-ARG-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13726-76-6 |
| Product name | BOC-ARG-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-ARG-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-ARG-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-ARG-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a protected amino acid monomer in peptide synthesis for preparing therapeutic peptides or proteins containing arginine residues | In solid-phase peptide synthesis (SPPS), the α-amino group of arginine is protected with a BOC (tert-butoxycarbonyl) group to prevent side reactions; subsequent deprotection is achieved via acidolysis (e.g., trifluoroacetic acid) |
| Biochemical Research | Applied in enzymology studies, receptor–ligand design, and construction of cell signaling pathway probes | BOC-arginine is incorporated during synthesis of biologically active peptide segments to maintain guanidinium side-chain stability and control reaction selectivity |
| Pharmaceutical Manufacturing | Employed as a key intermediate in the production of angiotensin-converting enzyme (ACE) inhibitors and antiviral peptide drugs | Serves as a protected arginine source in multi-step organic synthesis, participating in fragment coupling and cyclization reactions |
| Diagnostics Reagent Development | Used to synthesize peptide sequences that specifically recognize antibodies or enzyme substrates | Directional conjugation is performed using the BOC strategy to ensure functional integrity of the arginine residue within the assay system |
Manufacturing Quality Control of BOC-ARG-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (BOC-Arginine Content) | Acid-Base Titration with NaOH | Quantifies BOC-arginine by neutralizing the carboxylic acid group with standardized sodium hydroxide solution. |
| Water Content | Karl Fischer Titration | Determines water content via stoichiometric reaction between water, iodine, sulfur dioxide, and a base in methanol. |
| Residual Solvents (e.g., DCM, MeOH) | Gas Chromatography (GC) with FID | Separates and quantifies volatile organic solvents based on retention time and flame ionization detection response. |
| Heavy Metals | ICP-OES | Measures trace metal impurities (e.g., Pb, Cd, Ni) by atomizing the sample and detecting element-specific emission wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Related Substances | HPLC with UV Detection | Resolves and quantifies structurally related impurities (e.g., BOC-ornithine, arginine, di-BOC-arginine) using reversed-phase chromatography and UV absorbance. |
| Optical Rotation | Polarimetry | Measures specific rotation of plane-polarized light to confirm chiral purity and identity of L-arginine derivative. |
| pH (1% w/v aqueous solution) | pH Meter Measurement | Determines acidity/basicity of aqueous solution using calibrated glass electrode and reference electrode. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residual solids. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution by measuring angular variation in laser light scattering from dispersed particles. |
| Microbial Limits | Membrane Filtration and Plate Count | Detects and enumerates aerobic microorganisms using filtration, membrane transfer to agar media, and colony formation. |
| Appearance (Color and Clarity) | Visual Inspection against Standard Solutions | Evaluates physical appearance by comparing sample solution to reference standards under controlled lighting conditions. |
Technical Specifications of BOC-ARG-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168-172°C |
| Optical Rotation | [α]20/D = -6.5° to -5.5° |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-ARG-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-ARG-OH
Packaging of BOC-ARG-OH
Industrial BOC-ARG-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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