N-(tert-Butoxycarbonyl)-L-glutamine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13726-85-7 |
| Product name | N-(tert-Butoxycarbonyl)-L-glutamine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-(tert-Butoxycarbonyl)-L-glutamine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-(tert-Butoxycarbonyl)-L-glutamine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-(tert-Butoxycarbonyl)-L-glutamine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Protective amino acid monomer for peptide-based drug synthesis | Used as the Nα-tert-butoxycarbonyl (BOC)-protected derivative of L-glutamine in solid-phase peptide synthesis (SPPS) to construct therapeutic peptides containing glutamine residues (e.g., hormone analogs, antimicrobial peptides) |
| Biochemical Research | Chemically modified site for protein structure and function studies | Enables site-specific incorporation of glutamine residues and subsequent enzymatic or binding activity analysis via controlled BOC deprotection under acidic conditions (e.g., TFA/DCM) |
| Diagnostics Reagent Development | Preparation of antigenic peptides or reference standards for immunoassays | Serves as a key intermediate in synthesizing high-purity, sequence-defined peptides for in vitro diagnostic platforms such as ELISA and mass spectrometry calibration |
Manufacturing Quality Control of N-(tert-Butoxycarbonyl)-L-glutamine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies BOC-L-glutamine by reversed-phase HPLC with UV detection at 210 nm, using a calibrated standard curve. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separation on a chiral stationary phase and UV detection. |
| Water Content | Karl Fischer Titration | Determines water via coulometric or volumetric titration with iodine generated electrochemically or added stoichiometrically. |
| Residual Solvents | GC-FID | Identifies and quantifies common solvents (e.g., DCM, MTBE, MeOH) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after ignition at 500-600 C following sulfuric acid treatment. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light to confirm chiral integrity and concentration. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of dry powder via light scattering pattern analysis. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., de-BOC, hydrolysis products) using gradient HPLC. |
| pH of Aqueous Solution | Potentiometric Titration | Measures pH of a defined aqueous suspension or solution using a calibrated glass electrode. |
Technical Specifications of N-(tert-Butoxycarbonyl)-L-glutamine
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -4.0 to -3.0 deg (c=1, H2O) |
| Melting Point | 178 to 182 °C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-(tert-Butoxycarbonyl)-L-glutamine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-(tert-Butoxycarbonyl)-L-glutamine
Safety Information of N-(tert-Butoxycarbonyl)-L-glutamine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-(tert-Butoxycarbonyl)-L-glutamine
Industrial N-(tert-Butoxycarbonyl)-L-glutamine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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