4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid Bulk Supply for Industrial Use
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| CAS number | 137281-39-1 |
| Product name | 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 137281-39-1
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 137281-39-1 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 137281-39-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antiviral drug intermediates | Used in organic synthesis to construct target molecular structures |
| Biochemical Research | Development of enzyme inhibitors or biological probes | Applied in structural modification and activity optimization |
| Pesticides | Development of novel herbicides or fungicides | Used to introduce specific functional groups to enhance biological activity |
Manufacturing Quality Control of 137281-39-1
| Test Item | Common Testing Methods | Method Summary |
|---|---|---|
| Appearance and Properties | Visual Inspection, Melting Point Determination | Observe solid color, crystal form, and whether it clumps; determine melting point range using capillary method (typically 180–220°C) to assess purity and crystallization state. |
| Identification Test | Infrared Spectroscopy (IR), HPLC Retention Time Comparison, UV-Visible Spectroscopy (UV-Vis) | IR: Characteristic peaks such as amide C=O (1650–1700 cm⁻¹), aromatic rings (1600, 1580 cm⁻¹); HPLC: Match retention time with reference standard; UV: Show characteristic absorption at 250–300 nm due to conjugated pyrimidine ring structure. |
| Related Substances (Impurity Profile) | High Performance Liquid Chromatography (HPLC-UV/DAD) | Use a C18 column with gradient elution (water-acetonitrile/methanol), detect at 254 nm. Quantify degradation products, unreacted raw materials, isomers, etc. Typically require single impurity ≤ 0.5%, total impurities ≤ 1.0%. |
| Assay (Content Determination) | HPLC-UV Method (External Standard Method) | Quantitate using a known purity reference standard. Chromatographic conditions are the same as for related substances. Calculate main component content by peak area external standard method. Require ≥98.0% (on dry basis). |
| Water Content | Karl Fischer Titration (KF) | Determine trace water in samples using iodine-sulfur dioxide-pyridine-methanol system. Applicable to crystalline solids. Control water content ≤1.0% to prevent hydrolysis or stability reduction. |
| Residual Solvents | Gas Chromatography (GC-FID) | According to ICH Q3C standards, detect common organic solvents like methanol, ethanol, acetone, acetonitrile, etc. Use DB-624 or HP-INNOWAX column, headspace injection, quantitation limit meets pharmacopoeia requirements. |
| Heavy Metals and Elemental Impurities | ICP-MS or ICP-OES | Detect lead, cadmium, arsenic, mercury, etc., according to ICH Q3D. Sample is digested by microwave digestion before determination. Limits comply with FDA/EP/ChP standards (e.g., Pb ≤ 10 ppm). |
| Particle Size Distribution (if applicable) | Laser Diffraction Method | Used for API prior to formulation. Control particle size range (e.g., D90 < 50 μm), affecting solubility and formulation uniformity. |
| Crystal Form Analysis | X-ray Powder Diffraction (XRPD), Differential Scanning Calorimetry (DSC) | XRPD identifies characteristic diffraction peaks to confirm crystal form consistency; DSC measures fusion endothermic peak to determine if polymorphs or solvates exist. |
| pH Value (Aqueous Solution) | pH Meter Measurement | Dissolve sample into a saturated aqueous solution (or 0.1% w/v), measure pH value to evaluate acidic characteristics (due to benzoyl group, pH usually between 4–6). |
Technical Specifications of 137281-39-1
| Test Item | Specification |
|---|---|
| Appearance | White to gray to dark blue powder to crystal |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245–250 °C (decomposes) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.3% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 137281-39-1
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Industrial 137281-39-1 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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