N-Boc-L-valine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13734-41-3 |
| Product name | N-Boc-L-valine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Boc-L-valine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Boc-L-valine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Boc-L-valine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for peptide-based drug synthesis; used to incorporate L-valine residues into therapeutic peptides (e.g., antitumor peptides, hormone analogs) | Employed as an Nα-protected amino acid monomer in solid-phase peptide synthesis (SPPS); coupled to resin-bound peptide chains after activation with DIC/HOBt |
| Pharmaceutical R&D | Reagent for introducing the valine structural unit into chiral drugs and PROTAC molecules | Used in solution-phase peptide synthesis or fragment condensation reactions; amide bond formation performed using coupling systems such as DCC/DMAP or EDC·HCl/NHS |
| Biochemical Research | Precursor material for stable isotope labeling (e.g., SILAC) in proteomics (e.g., ¹³C/¹⁵N-labeled Boc-L-valine) | Applied as a cellular metabolic label in sterile culture media; incorporated into newly synthesized proteins following cellular uptake |
| Fine Chemicals | Starting material for synthesizing chiral catalyst ligands (e.g., oxazoline-based ligands) | Converted to chiral oxazoline ligand scaffolds via decarboxylation and cyclization with diazomethane, or condensation with aldehydes |
Manufacturing Quality Control of N-Boc-L-valine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, with quantitation based on relative peak areas. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Residual Solvents | GC-FID | Gas chromatographic separation followed by flame ionization detection, quantified against solvent standards. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion, based on characteristic atomic emission spectra intensities. |
| Chloride Impurity | Ion Chromatography | Anion exchange separation with suppressed conductivity detection for quantitative chloride determination. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by weighing of inorganic residue after sulfuric acid treatment. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution of known concentration and path length. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Determination using calibrated glass electrode in a saturated aqueous suspension or clear solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of angular scattering pattern of laser light passed through a dispersed sample to calculate size distribution. |
| Microbial Contamination | Membrane Filtration | Filtration of sample solution, followed by culture on nutrient media and colony enumeration. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient reversed-phase chromatography with UV detection. |
Technical Specifications of N-Boc-L-valine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Optical Rotation | -6.2±0.5° (c=1, in 1N HCl) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Boc-L-valine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Boc-L-valine
Packaging of N-Boc-L-valine
Industrial N-Boc-L-valine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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