China Factory Direct
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| CAS number | 137348-86-8 |
| Product name | Di-tert-butyl N,N-diisopropylphosphoramidite |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals/Chemicals | Phosphoramidite reagent for oligonucleotide synthesis | Used in solid-phase phosphoramidite chemical synthesis |
| Pharmaceuticals/Chemicals | Preparation of di-tert-butyl protected phosphoramidite monomers | Applied in liquid-phase organic synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies main component by retention time and peak area comparison against certified reference standard. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detects and quantifies volatile organic solvents based on partitioning into headspace and GC separation. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Measures water via electrochemical generation of iodine reacting stoichiometrically with water in anhydrous medium. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Determines acidic impurities by titration with standardized sodium hydroxide using phenolphthalein indicator. |
| Phosphorus Content | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Quantifies total phosphorus after acid digestion by measuring characteristic atomic emission lines. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separates and quantifies chloride ions using ion-exchange column and suppressed conductivity detection. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detects trace heavy metals after microwave-assisted digestion by elemental mass-to-charge ratio measurement. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measures non-volatile inorganic residue after high-temperature ashing at 600 C. |
| Optical Rotation | Polarimetry | Determines specific rotation using plane-polarized light to assess chiral purity and enantiomeric excess. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against standard reference under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| pH of Aqueous Solution | pH Meter Measurement | Measures hydrogen ion activity in a defined aqueous suspension or solution using calibrated glass electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.440–1.450 |
| Relative Density (20°C/25°C) | 0.92–0.94 g/cm³ |
| Odor | Characteristic mild phosphorous odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.