2-(Trimethylsilyl)pyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13737-04-7 |
| Product name | 2-(Trimethylsilyl)pyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-(Trimethylsilyl)pyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-(Trimethylsilyl)pyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-(Trimethylsilyl)pyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key building block for synthesizing nitrogen-containing heterocyclic drugs (e.g., antitumor agents, kinase inhibitors) | Acts as a nucleophile in C-2 functionalization of pyridine rings; commonly employed in lithiation–electrophilic substitution or cross-coupling reactions with haloarenes |
| Organic Synthesis | Protects the pyridyl nitrogen atom and activates the C-2 position for selective substitution | Undergoes nitrogen deprotonation/silyl migration with n-butyl lithium at low temperature to generate 2-lithio-1-trimethylsilylpyridine, used for subsequent carbon–carbon bond formation |
| Materials Science | Preparation of metal complexes bearing pyridyl ligands for organic light-emitting diodes (OLEDs) | Enables highly regioselective C–H activation via silyl-directed directed metallation, applied in synthesizing phosphorescent ligands for Ir(III) and Pt(II) complexes |
| Pesticide Development | Core structural unit for constructing novel pyridine-based insecticides and plant growth regulators | Serves as a stable, operationally convenient platform for C-2 functionalization; active side chains are introduced via desilylation, oxidation, amination, and other derivatization steps |
Manufacturing Quality Control of 2-(Trimethylsilyl)pyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies 2-trimethylsilylpyridine peak area relative to a calibration curve using an internal or external standard. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Separates and quantifies volatile organic solvents based on retention time and peak area using calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemically determines water content via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Acidity (as HCl) | Acid-Base Titration with Potentiometric End-Point Detection | Neutralizes acidic impurities with standardized NaOH; endpoint detected by pH change. |
| Residue on Ignition | Gravimetric Analysis after High-Temperature Ashing | Measures non-volatile inorganic residue remaining after controlled combustion at 700-800 C. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Ionizes sample and detects elemental isotopes based on mass-to-charge ratio with ultra-trace sensitivity. |
| Chloride Ion | Ion Chromatography (IC) with Conductivity Detection | Separates chloride anions chromatographically and quantifies via conductivity response relative to calibration standards. |
| Appearance | Visual Inspection against Standard Reference | Assesses physical state, color, and clarity by comparison to defined reference under controlled lighting conditions. |
| Density | Oscillating U-Tube Densitometry | Determines density from the resonant frequency of a vibrating U-shaped tube filled with sample. |
| Refractive Index | Digital Refractometry | Measures angle of light refraction at air-sample interface to calculate refractive index at specified temperature. |
| Boiling Point Range | Capillary Gas Chromatography with Temperature Programming | Identifies volatility profile and boiling point range from elution temperatures under controlled GC oven ramp. |
| Organosilicon Impurities (e.g., hexamethyldisiloxane) | Gas Chromatography-Mass Spectrometry (GC-MS) | Separates volatile impurities and identifies/quantifies them via characteristic mass spectra and retention times. |
Technical Specifications of 2-(Trimethylsilyl)pyridine
| Test Item | Specification |
|---|---|
| Appearance | Light yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.505–1.515 |
| Relative Density (20°C/4°C) | 0.870–0.890 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-(Trimethylsilyl)pyridine
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NMR Spectra of 2-(Trimethylsilyl)pyridine
Packaging of 2-(Trimethylsilyl)pyridine
Industrial 2-(Trimethylsilyl)pyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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