China Factory Direct
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| CAS number | 13749-61-6 |
| Product name | N-ISOPROPYLMETHACRYLAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeMaterial GradeElectronic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Polymers | Synthesis of thermosensitive polymers | Used as a comonomer in free-radical polymerization to produce poly(N-isopropylmethacrylamide) hydrogels exhibiting a lower critical solution temperature (LCST) |
| Pharmaceuticals | Controlled drug delivery carrier | Copolymerized with other monomers to form thermosensitive nanospheres or hydrogels for body-temperature-triggered drug release systems |
| Biotechnology | Biosensor material | Applied as a sensing layer material, leveraging its phase-transition behavior to respond to temperature changes in biomolecular detection |
| Coatings Industry | Smart coating additive | Incorporated as a functional monomer into coating formulations to impart temperature responsiveness (e.g., self-regulating transparency or hydrophobicity) |
| Electronic Materials | Functional component in photoresists | Employed as a thermosensitive crosslinker or sensitizer in semiconductor photolithography to modulate development behavior |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies N-isopropylmethacrylamide peak area relative to an internal standard or external calibration curve. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration using iodine-based reagent stoichiometry. |
| Acid Number | Acid-Base Titration with NaOH | Determines acidic impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Color (APHA) | Visual Comparison or Spectrophotometry | Compares sample color intensity against APHA platinum-cobalt standard solutions at 455 nm. |
| Specific Gravity | Digital Density Meter | Measures mass per unit volume at controlled temperature using oscillating U-tube principle. |
| Refractive Index | Refractometry | Determines ratio of light velocity in air vs. sample using critical angle measurement at 20 C. |
| UV Absorbance (at 220 nm) | UV-Vis Spectrophotometry | Quantifies absorbance at specified wavelength to detect conjugated impurities or degradation products. |
| Peroxide Value | Iodometric Titration | Measures peroxides via oxidation of iodide to iodine, followed by titration with sodium thiosulfate. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantifies total heavy metals after wet digestion by measuring atomic absorption at element-specific wavelengths. |
| Residual Solvents (e.g., toluene, methanol) | Headspace Gas Chromatography (HS-GC) | Separates and quantifies volatile solvents using headspace sampling and GC-FID detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 58-62°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic, mild |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.