China Factory Direct
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| CAS number | 137553-42-5 |
| Product name | 2-FLUORO-4-IODOBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate for anticancer drugs and tyrosine kinase inhibitors | Biphenyl structure construction via Suzuki coupling using the iodine atom; conversion of the nitrile group to a tetrazole ring or amide structure. |
| Agrochemicals | Building block for synthesis of agrochemically active molecules | Introduction of the fluoroiodobenzonitrile scaffold via coupling reactions for synthesis of novel herbicides or insecticides. |
| Materials Science | Intermediate for organic electroluminescent materials (OLEDs) and functional dyes | Arylation modification leveraging iodine-group reactivity to construct π-conjugated systems with tailored optoelectronic properties. |
| Organic Synthesis | Preparation of specially functionalized aromatic compounds | Dual-functional reagent enabling selective transformations of the iodine and nitrile groups to synthesize complex fluorinated benzoic acid derivatives. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-254 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., unreacted intermediates, isomers, dehalogenated by-products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., DMF, THF, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in methanol-based reagent. |
| Inorganic Halides (Cl-, Br-) | Ion Chromatography (IC) | Separates and quantifies halide anions using suppressed conductivity detection after anion-exchange separation. |
| Heavy Metals | ICP-MS | Measures trace metallic impurities (e.g., Pb, Cd, Hg, Ni) by plasma ionization and mass spectrometric detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard references. |
| Bulk Density | Tap Density Tester | Measures mass per unit volume of freely settled and tapped powder using standardized cylinder and tapping mechanism. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution by analyzing angular scattering pattern of laser beam passed through dispersed sample. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral impurities or degradation products in solution. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.