3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 137724-66-4 |
| Product name | 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel chlorofluoro-containing insecticides and fungicides | Used to construct biologically active molecules containing heterocyclic or aryl thiourea structures via reaction of the isothiocyanate group with amines or alcohols |
| Pharmaceuticals | Intermediate for synthesizing protease inhibitors, antitumor agents, and targeted therapeutic compounds | Applied as an electrophilic reagent in covalent conjugation with amino acid residues (e.g., cysteine) to build drug molecule scaffolds |
| Chemical Reagents | Highly reactive reagent for introducing the isothiocyanate functional group in organic synthesis | Employed as a coupling reagent in multistep syntheses to prepare thiourea derivatives or functionalized molecular probes |
Manufacturing Quality Control of 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., starting materials, intermediates, degradation products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., toluene, THF, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent. |
| Chloride Content | Ion Chromatography (IC) | Quantifies chloride ion impurity by separation on anion-exchange column with conductivity detection. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Acid Value | Acid-Base Titration | Determines acidic impurities by titration with standardized NaOH solution using phenolphthalein indicator. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against specified criteria (white to off-white crystalline solid). |
| Loss on Drying | Gravimetric Analysis | Determines volatile matter by measuring weight loss after drying under controlled vacuum and temperature conditions. |
| Residue on Ignition | Sulfated Ash Test | Quantifies non-volatile inorganic residue after high-temperature ignition following sulfuric acid treatment. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity (if applicable) by determining rotation of plane-polarized light in solution at specified concentration and wavelength. |
Technical Specifications of 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Refractive Index (n20/D) | 1.575–1.585 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
Safety Information of 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE
Industrial 3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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