China Factory Direct
|
|
| CAS number | 1378388-19-2 |
| Product name | 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as an intermediate in the synthesis of anticancer or anti-inflammatory drug candidates | Multi-step organic synthesis, commonly involving reduction, condensation, or coupling reactions to construct complex molecular frameworks |
| Organic Synthesis | Used as a precursor for functional molecules containing the naphthone structure | Introduction of specific substituents via functional group transformations (e.g., Suzuki coupling with bromoaryl substrates) |
| Medicinal Chemistry | Used as a lead compound for structure–activity relationship (SAR) exploration and optimization | Side-chain modification or ring system modification based on its core scaffold to enhance biological activity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and detection of structurally related impurities (e.g., starting materials, dehalogenated analogs, hydrolysis products) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, toluene, DMF) by gas chromatography with flame ionization detection against internal standard calibration. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Pd) after acid digestion, leveraging high sensitivity and isotopic resolution of inductively coupled plasma mass spectrometry. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture in anhydrous methanol-based electrolyte. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration (700–800 °C) followed by precise weighing of residual non-volatile matter. |
| Chloride/Bromide Content | Ion Chromatography (IC) | Quantitative separation and conductivity detection of halide anions (Cl⁻, Br⁻) released via alkaline oxidative combustion or microwave-assisted extraction. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry or wet dispersed particle size based on angular scattering intensity of laser light, reported as D10/D50/D90 values. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection via controlled heating of a capillary-packed sample, identifying onset and range of solid-to-liquid phase change. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light, indicating chiral purity and absence of racemization or enantiomeric impurities. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of surface acidity/basicity by pH electrode measurement of a standardized suspension (e.g., 1% w/v in water). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.