China Factory Direct
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| CAS number | 138-52-3 |
| Product name | D-(-)-Salicin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in the synthesis of salicylate-based drugs as a precursor for anti-inflammatory, analgesic, and antipyretic agents | Chemical synthesis: Hydrolysis of salicin to produce salicylic acid |
| Biotechnology | Employed as a reference standard or molecular probe in bioactivity studies | Extraction and purification: Isolated from plant material followed by chromatographic purification |
| Food additives | Used as a natural flavoring agent (within permitted limits) | Natural extraction: Extracted from plant sources such as willow bark and subsequently refined |
| Chemical reagents | Used as a reference standard in laboratory analysis and chemical research | Refinement and standardization: Purified via recrystallization or column chromatography to meet reagent-grade specifications |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Thin-Layer Chromatography (TLC) | Using reference standards, qualitative identification is performed by comparing the Rf values of the test sample and the reference standard after development and visualization. Silica gel G plates are commonly used, with developing systems such as ethyl acetate-methanol-water (e.g., 8:2:1). Vanillin-sulfuric acid reagent may be used as a visualizing agent. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase under isocratic or gradient elution. Detection is carried out using a UV detector (typically around 275 nm), and quantification is performed by the external standard method, offering high sensitivity and good reproducibility. |
| Impurity Testing | HPLC Method | Related substances (such as other phenolic glycosides or degradation products) are examined using HPLC by the main component self-reference method or impurity reference substance method to evaluate sample purity. |
| Moisture Content | Loss on Drying (LOD) or Karl Fischer Titration | The drying method is suitable for general moisture determination; the Karl Fischer method is more accurate and appropriate for trace moisture analysis, ensuring the stability of salicin is not affected by moisture. |
| Total Ash and Acid-Insoluble Ash | Ignition Method | Determines the total residue remaining after high-temperature incineration (total ash) and the portion insoluble in hydrochloric acid (acid-insoluble ash), used to control inorganic impurities. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detects levels of harmful elements such as lead, cadmium, arsenic, and mercury to ensure compliance with pharmacopeial or food-grade safety standards. |
| Pesticide Residues | Gas Chromatography-Mass Spectrometry (GC-MS) or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | Performs multi-residue analysis of pesticide residues (e.g., organochlorines, organophosphates) in extracts to ensure the safety of raw material sources. |
| Microbial Limits | Microbiological Culture Methods | Tests total bacterial count, molds and yeasts count, and specified pathogens (e.g., Escherichia coli, Salmonella) according to requirements of the Chinese Pharmacopoeia or international pharmacopoeias. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 197–202°C |
| Optical Rotation | -64.0 to -60.0° (c=1, in water) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.