China Factory Direct
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| CAS number | 138021-87-1 |
| Product name | FMOC-CYS(ME)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for solid-phase peptide synthesis | Used as an amino-protecting group in solid-phase peptide synthesis |
| Chemical Reagents | Amino protection in organic synthesis reactions | Amino groups protected via fluorenylmethyloxycarbonyl (Fmoc) chemistry |
| Biotechnology | Directed synthesis of proteins or peptides | Standard amino acid precursor in automated solid-phase synthesizers |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase, with detection by UV; L-isomer content determined relative to D-isomer peak area. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to quantify water via stoichiometric reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to identify and quantify volatile organic solvents (e.g., DMF, DCM, MeOH). |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration (700-800 C) and weighing of residual residue. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 20 C using sodium D-line (589 nm), normalized to concentration and path length. |
| pH of Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode and pH meter. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deprotected Fmoc-Cys, oxidation products) using gradient HPLC with UV detection. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on angular scattering intensity of laser beam. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Counterion Content (e.g., Na+) | ICP-OES | Quantification of sodium or other counterions after sample dissolution and dilution, using inductively coupled plasma optical emission spectrometry. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152 °C |
| Optical Rotation | -43.0 to -41.0 ° (c=1, in DMF) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.