China Factory Direct
|
|
| CAS number | 138060-07-8 |
| Product name | 3-Aminopiperidine dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral intermediate for synthesizing active pharmaceutical ingredients containing a piperidine ring (e.g., NK1 receptor antagonists, kinase inhibitors) | Used as a chiral building block in multi-step organic synthesis, including coupling reactions, amidation, and reductive amination |
| Agrochemical R&D | Key chiral intermediate for structural modification of novel insecticides and fungicides | Applied to introduce nitrogen-containing heterocyclic structures, enhancing target enzyme selectivity and metabolic stability |
| Materials Science | Functional monomer for synthesizing ion-conductive membranes or chiral separation materials | Attached to polymeric backbones via the amino group to modulate hydrophilicity and chiral recognition capability |
| Test Item | Common Test Method | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of caking in the sample under natural or standard lighting to determine compliance with specifications. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample spectrum with a reference spectrum; confirm molecular structure consistency based on characteristic absorption peaks. |
| Proton Nuclear Magnetic Resonance (¹H-NMR) | Confirm compound structure by analyzing the position, integral area, and splitting pattern of characteristic peaks in the hydrogen spectrum. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column with UV detection and external or internal standard method to determine the content of the active ingredient and assess purity. |
| Non-aqueous Titration | Titrate the free base form of amino groups using a perchloric acid standard solution in a non-aqueous solvent (e.g., glacial acetic acid) to calculate the content. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic elution to detect and quantify process impurities and degradation products; total impurity levels are typically required to be below specified limits. |
| Water Content | Karl Fischer Titration | Determine moisture content using a Karl Fischer titrator; suitable for compounds containing water, including hydrates. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Method | Dry the sample at a specified temperature for a defined period, measure weight loss before and after drying, and calculate the percentage weight loss. |
| Sulfated Ash (Residue on Ignition) | Gravimetric Method | Char the sample, treat with sulfuric acid, then ignite at high temperature; weigh the residual inorganic matter to assess inorganic impurity content. |
| Chloride Test | Ion Chromatography (IC) or Argentometric Method | Detect excess or free chloride ions in hydrochloride salts to ensure compliance with pharmacopoeial or quality standards. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine residual levels of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with ICH or pharmacopoeial limits. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRPD) | Analyze the crystalline structure of solid samples to identify polymorphic forms and ensure batch-to-batch consistency. |
| Particle Size Distribution | Laser Diffraction Analysis (LDA) | Measure particle size distribution based on laser scattering principles; influences solubility and formulation performance. |
| pH Value | pH Meter Method | Prepare an aqueous solution of specified concentration and measure its acidity or alkalinity using a calibrated pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–220 °C (decomposes) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.