(R)-3-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 138108-72-2 |
| Product name | (R)-3-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 138108-72-2
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 138108-72-2 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 138108-72-2
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of antiviral agents (e.g., HIV protease inhibitors) and central nervous system drugs | Multi-step organic synthesis, typically involving asymmetric hydrogenation or chiral resolution to construct the target molecular scaffold |
| Pharmaceuticals | Used to construct biologically active molecules containing a pyrrolidine moiety for drug candidate development | Condensation or coupling with carboxylic acids, aldehydes, or ketones; Boc protection enables subsequent deprotection |
| Chemical Reagents | Used as a chiral building block in combinatorial chemistry and high-throughput screening | Boc group protects the amino functionality; the hydroxymethyl group can be further derivatized to esters, ethers, or halides |
| Agrochemicals | Used to synthesize chiral agrochemical precursors with biological activity | Coupling with heterocyclic or aromatic structures to build active ingredients targeting insect neuronal receptors |
Manufacturing Quality Control of 138108-72-2
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, relative to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and enantiomeric excess calculation. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generation to determine trace water based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion and plasma ionization. |
| Residual BOC Reagent | GC-MS | Detection and quantification of di-tert-butyl dicarbonate and its degradation products using gas chromatography-mass spectrometry. |
| Acidity/Basicity | Acid-Base Titration | Neutralization titration with standardized NaOH or HCl to determine total acidic or basic impurities. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient reverse-phase HPLC with UV detection. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues after microwave digestion, using optical emission from excited plasma atoms. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry or wet dispersed particle size via light scattering pattern analysis and Mie theory calculation. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using controlled heating and visual observation. |
| Loss on Drying | Gravimetric Analysis | Mass loss measurement after drying under controlled temperature and vacuum, indicating volatile content including moisture and solvents. |
Technical Specifications of 138108-72-2
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | +17.0 to +21.0 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 62.0 to 66.0 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 138108-72-2
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 138108-72-2
Packaging of 138108-72-2
Industrial 138108-72-2 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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