China Factory Direct
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| CAS number | 13811-71-7 |
| Product name | (2S,3S)(-)-Dihydroxybutane-1,4-dioic acid diethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate | Used as a chiral auxiliary in asymmetric synthesis for stereoselective production of drugs such as β-lactam antibiotics |
| Chemical Research | Asymmetric catalytic reactions | Applied as a chiral ligand or precursor in transition metal-catalyzed asymmetric hydrogenation, epoxidation, and related reactions |
| Fine Chemicals | Chiral resolving agent | Employed in racemate resolution processes, enabling preparation of optically pure compounds via diastereomeric crystallization |
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample under natural light or standard light sources to check if it is a colorless to slightly yellow clear liquid without visible impurities. |
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample using an infrared spectrometer and compare it with the standard spectrum to confirm the presence of characteristic functional groups (such as ester groups, hydroxyl groups, etc.). |
| Content Determination | Gas Chromatography (GC) | Use a capillary gas chromatography column with a hydrogen flame ionization detector (FID) for detection. Quantify using internal standard method or external standard method to determine the content of D-(-)-tartaric acid diethyl ester. |
| Specific Rotation | Polarimetry | Determine the optical rotation of the sample solution using a polarimeter at the specified wavelength (usually sodium D line, 589 nm) and temperature to calculate the specific rotation, verifying its optical purity and configuration. |
| Moisture | Karl Fischer Titration | Accurately determine the trace moisture content in the sample using either the volumetric or coulometric Karl Fischer titration method. |
| Related Substances (Impurities) | Gas Chromatography (GC) or High-Performance Liquid Chromatography (HPLC) | Separate potential impurities (such as unreacted raw materials, by-products, degradation products, etc.) in the sample using GC or HPLC. Quantify using area normalization method or main component self-reference method with correction factors. |
| Acid Value / Free Acid | Acid-Base Titration | Determine the free acid content in the sample using phenolphthalein as the indicator and standard sodium hydroxide solution, reflecting the completeness of the esterification reaction or hydrolysis condition. |
| Residual Solvents | Gas Chromatography (Headspace or Direct Injection) | Detect possible residual organic solvents (such as ethanol, ether, dichloromethane, etc.) in the sample according to ICH Q3C guidelines using GC. |
| Heavy Metals | Thioacetamide Method or Atomic Absorption Spectrometry (AAS) | Perform heavy metal limit testing according to pharmacopoeia monographs to control heavy metal impurities introduced during catalysis or production processes. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC) |
| Optical Rotation | -8.0 to -9.0 deg (c=1, in ethanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.416 to 1.420 |
| Relative Density (20°C/25°C) | 1.070 to 1.085 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.