7-Methoxy-1-naphthylacetonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 138113-08-3 |
| Product name | 7-Methoxy-1-naphthylacetonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7-Methoxy-1-naphthylacetonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7-Methoxy-1-naphthylacetonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7-Methoxy-1-naphthylacetonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for the synthesis of the antiplatelet drug ticagrelor | In the ticagrelor synthesis route, 2-(7-methoxynaphthalen-1-yl)acetonitrile undergoes NaBH₄/CuCl-catalyzed hydrogenation reduction to the corresponding amine, followed by condensation with chloroacetone to construct the triazolopyrimidine core scaffold, via sequential reduction, cyclization, and phosphorylation steps |
| Organic Synthesis | Starting material for constructing naphthalene-containing heterocyclic compounds | Participates in Knoevenagel condensation, Pinner reaction, or nucleophilic substitution with sodium azide followed by cyclization to prepare naphthyl-substituted triazole, tetrazole, and imidazole derivatives |
Manufacturing Quality Control of 7-Methoxy-1-naphthylacetonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD or UPLC-MS | Separation and identification/quantification of structurally related impurities using gradient HPLC with diode-array detection or mass spectrometric confirmation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, toluene, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic detection for high sensitivity. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in solution, often following sample dissolution and dilution. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid phase transition temperature using calibrated capillary instrumentation per USP <741>. |
| Appearance (Color & Clarity) | Visual Inspection in Solution | Assessment of solution clarity and color (e.g., in acetonitrile or methanol) against standard references (e.g., APHA/Hazen scale). |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile inorganic residue remaining after controlled high-temperature ashing of the sample. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to detect chiral impurities or enantiomeric excess (if applicable). |
Technical Specifications of 7-Methoxy-1-naphthylacetonitrile
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116 °C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7-Methoxy-1-naphthylacetonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7-Methoxy-1-naphthylacetonitrile
Packaging of 7-Methoxy-1-naphthylacetonitrile
Industrial 7-Methoxy-1-naphthylacetonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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