China Factory Direct
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| CAS number | 138564-58-6 |
| Product name | 2-Amino-5-methyl-3-thiophenecarbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of anticancer agents (e.g., CDK inhibitors) | Used in drug molecule construction via nucleophilic substitution, cyclization, or coupling reactions |
| Pesticides | Structural building block for synthesizing novel fungicides or herbicides | Introduced as a heterocyclic scaffold into active molecules and converted to target compounds through multistep organic synthesis |
| Organic Synthesis | General-purpose intermediate for constructing thiophene-based heterocyclic compounds | Applied in functional molecule synthesis, including Suzuki coupling and Vilsmeier-Haack formylation |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities under natural or standard lighting conditions. |
| Purity (Active Component Content) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) and UV detector (typically at 254 nm or 280 nm); quantify the target compound by comparison with a reference standard. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR and ¹³C-NMR to identify molecular structure, confirming characteristic peaks for functional groups such as amino, cyano, methyl, and thiophene ring. |
| Structural Confirmation | Mass Spectrometry (MS) | Determine the molecular ion peak using electrospray ionization (ESI) or electron ionization (EI), analyze fragment ions to verify molecular weight and confirm structure. |
| Water Content | Karl Fischer Titration | Accurately measure water content based on the reaction of iodine and sulfur dioxide with water in an anhydrous environment. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, acetonitrile) according to ICH guidelines, using an FID detector. |
| Melting Point | Melting Point Determination (Capillary Method or Automated Melting Point Apparatus) | Measure the temperature range at which the compound transitions from solid to liquid, used for preliminary assessment of purity and consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine residual levels of harmful metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical or industrial safety standards. |
| Cyano Group Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirm the presence of the cyano group by identifying its characteristic absorption peak (e.g., —C≡N stretching vibration at 2200–2260 cm⁻¹). |
| Amino Group Confirmation | Chemical Colorimetric Test or pH Indicator Method | Utilize the basic nature of amino groups; perform qualitative confirmation via acid-base titration or color-forming reactions such as diazotization with nitrous acid. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Purity | >=98.5% |
| Melting Point | 128–132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.