1-(tertbutoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yltrifluoromethanesulfonate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 138647-49-1 |
| Product name | 1-(tertbutoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yltrifluoromethanesulfonate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 138647-49-1
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 138647-49-1 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 138647-49-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key Intermediate | Used to synthesize piperidine or tetrahydropyridine ring derivatives, commonly applied in the R&D and manufacturing of proteolysis-targeting chimeras (PROTACs) and other novel drug molecules. |
| Organic Synthesis | Substrate for Suzuki-Miyaura Cross-Coupling | Serves as a coupling partner for organoboron reagents under palladium catalysis to construct carbon–carbon bonds, introducing the 3,6-dihydropyridine structural motif into target molecules. |
| Organic Synthesis | Substrate for Heck Cross-Coupling | Reacts with alkenes under palladium catalysis to construct pyridine or dihydropyridine derivatives bearing alkene substituents. |
| Organic Synthesis | Reagent for Cross-Coupling Reactions | Leverages the triflate group (–OTf) as an effective leaving group to form carbon–carbon or carbon–heteroatom bonds, enabling construction of complex molecular frameworks. |
| Fine Chemicals | Precursor for Primary Alcohol Functionalization | Prepared via sulfonation of N-Boc-1,2,3,6-tetrahydropyridin-4-ol; converts the hydroxyl group on the pyridine ring into a more reactive leaving group to facilitate subsequent derivatization reactions. |
Manufacturing Quality Control of 138647-49-1
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection against reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., toluene, THF, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine consumption in pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using suppressed conductivity detection after aqueous extraction. |
| Residual Catalyst (Pd) | ICP-OES | Measures palladium residue post-catalytic synthesis by inductively coupled plasma optical emission spectroscopy. |
| Optical Rotation | [alpha]D Measurement | Determines specific rotation using sodium D-line light to confirm chiral integrity and absence of racemization. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine volume-weighted particle size distribution. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after controlled heating under specified time/temperature/vacuum conditions. |
Technical Specifications of 138647-49-1
| Test Item | Specification |
|---|---|
| Appearance | Yellow to beige solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 138647-49-1
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 138647-49-1
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Industrial 138647-49-1 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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