(2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 138716-20-8 |
| Product name | (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate for the antifungal drug fluconazole and related triazole antifungals | Serves as a bridging reagent in Michael addition reactions with 1,2,4-triazoles or imidazoles to construct 1,2,4-triazolyl- or imidazolyl-propanol scaffolds |
| Pharmaceutical Industry | Synthetic research of novel triazole antifungal agents (e.g., itraconazole derivatives, voriconazole analogues) | Undergoes structural modification via its α,β-unsaturated ketone moiety to introduce aryl and heterocyclic side chains through nucleophilic addition, thereby optimizing pharmacological activity and pharmacokinetic properties |
| Chemical Reagents | Building block for laboratory-scale organic synthesis | Used in addition, reduction, or cyclization reactions to prepare fluorinated chalcone derivatives, pyrrolines, or pyridine-based heterocycles for drug discovery and chemical research |
Manufacturing Quality Control of (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength based on peak area comparison against reference standard. |
| Related Substances | HPLC-DAD or HPLC-MS | Separates and detects impurities using gradient HPLC coupled with diode array or mass spectrometric detection; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents by gas chromatography with flame ionization detection using calibrated standard solutions. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation in aqueous mobile phase. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature incineration of sample and subsequent weighing of the ash. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of phase change in capillary tube. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral molecules in solution at specified concentration, path length, and wavelength (e.g., 589 nm). |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension of compound in water using calibrated glass electrode system. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension by analyzing angular variation in laser light scattering intensity. |
| Bulk Density | Tap Density Tester | Measures mass per unit volume of powder after standardized tapping procedure to assess flow and packing characteristics. |
Technical Specifications of (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one
Industrial (2E)-3-(DiMethylaMino)-1-(4-fluorophenyl)prop-2-en-1-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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