Fmoc-3-(2-Naphthyl)-D-alanine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 138774-94-4 |
| Product name | Fmoc-3-(2-Naphthyl)-D-alanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-3-(2-Naphthyl)-D-alanine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-3-(2-Naphthyl)-D-alanine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-3-(2-Naphthyl)-D-alanine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as an amino acid derivative in Fmoc-based peptide synthesis | Applied in solid-phase or solution-phase peptide synthesis as an Fmoc-protected non-natural amino acid component to construct peptide fragments containing naphthyl groups |
| Biochemical Research | Used to study protein structure and function, particularly hydrophobic interactions | Applied in chemical synthesis to incorporate 2-naphthyl-containing D-alanine residues for investigating their effects on peptide folding, stability, and receptor binding |
| Chemical Synthesis | Used as a chiral building block for synthesizing complex natural products or pharmaceutical intermediates | Applied in deprotection, coupling, or cyclization reactions as an intermediate for constructing alanine scaffolds bearing aryl substituents |
Manufacturing Quality Control of Fmoc-3-(2-Naphthyl)-D-alanine
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Inspect the sample's color, physical state (e.g., white to off-white crystalline powder) and presence of foreign particles by naked eye observation to preliminarily assess whether the physical characteristics meet requirements. |
| Identification | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) |
IR: Compare the sample’s infrared absorption spectrum with the reference standard spectrum for consistency; ¹H NMR: Analyze characteristic chemical shifts and coupling constants to confirm molecular structure; HPLC-MS: Use retention time and mass-to-charge ratio (m/z) for qualitative identification. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with acetonitrile-water or methanol-water as mobile phase, detect at UV detector (typically 220–280 nm), and calculate the main component content using external standard method or area normalization method. Requirement is generally ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Same conditions as content determination or optimized gradient elution program; separate and quantify potential impurities (e.g., starting materials, by-products, degradation products). Individual impurity should not exceed 0.5%, and total impurities should not exceed 1.0%. |
| Specific Rotation | Polarimeter Method | Prepare a solution of specified concentration (e.g., 1% w/v in DMF or methanol), measure optical rotation under defined temperature (e.g., 20°C) and wavelength (sodium D line, 589 nm), then calculate specific rotation to confirm chiral purity (D-configuration). |
| Water Content | Karl Fischer Titration | Determine moisture content using either volumetric or coulometric Karl Fischer titration. Typically requires ≤0.5% to ensure product stability and efficiency in subsequent synthetic reactions. |
| Residual Solvents | Gas Chromatography (GC) | Based on ICH Q3C guidelines, use headspace injection or direct injection GC-FID/MS to detect potentially residual organic solvents (e.g., dichloromethane, DMF, methanol), ensuring compliance with established limits. |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature range using a melting point apparatus as an auxiliary purity indicator. The typical melting range should match literature values (e.g., approximately 140–145°C, depending on batch). |
Technical Specifications of Fmoc-3-(2-Naphthyl)-D-alanine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | +11.0 to +14.0° (c=1, DMF) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-3-(2-Naphthyl)-D-alanine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-3-(2-Naphthyl)-D-alanine
Safety Information of Fmoc-3-(2-Naphthyl)-D-alanine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Fmoc-3-(2-Naphthyl)-D-alanine
Industrial Fmoc-3-(2-Naphthyl)-D-alanine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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