Fmoc-N-methyl-D-phenylalanine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 138775-05-0 |
| Product name | Fmoc-N-methyl-D-phenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-N-methyl-D-phenylalanine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-N-methyl-D-phenylalanine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-N-methyl-D-phenylalanine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for synthesizing peptide-based therapeutics and biologically active molecules | Introduction of N-methylphenylalanine residues into solid-phase or solution-phase peptide synthesis to enhance metabolic stability and membrane permeability |
| Biochemical Research | Construction of model peptide segments containing N-methyl amino acids to study conformational constraints and protease resistance | Fmoc-based solid-phase peptide synthesis (SPPS), followed by deprotection and coupling at specific positions along the peptide chain |
| Medicinal Chemistry | Synthesis of precursors for small-molecule inhibitors targeting receptors such as GPCRs and kinases | Connection to other pharmacophores via amide or ester bonds, enabling construction of complex molecular scaffolds through condensation or coupling reactions |
Manufacturing Quality Control of Fmoc-N-methyl-D-phenylalanine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 260-280 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, DCM, methanol) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20-25 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, As, Hg) by inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-OES | Detection of residual Pd catalyst by inductively coupled plasma optical emission spectroscopy following microwave-assisted acid digestion. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assessment of physical form, color, and homogeneity under controlled white light against established reference standards. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie scattering theory applied to laser diffraction patterns. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic microorganisms by filtration, membrane transfer to agar media, and colony counting after incubation. |
Technical Specifications of Fmoc-N-methyl-D-phenylalanine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | +54.0 to +60.0° (c=1, DMF) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-N-methyl-D-phenylalanine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-N-methyl-D-phenylalanine
Safety Information of Fmoc-N-methyl-D-phenylalanine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Fmoc-N-methyl-D-phenylalanine
Industrial Fmoc-N-methyl-D-phenylalanine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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