China Factory Direct
|
|
| CAS number | 13893-53-3 |
| Product name | 2-Amino-2,3-dimethylbutyronitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic intermediate in the preparation of certain pharmaceuticals | Converted into target pharmaceutical molecules via chemical reaction |
| Pesticides | Used as a key intermediate in pesticide synthesis | Integrated into specific organic synthesis pathways to generate target compounds with insecticidal or fungicidal activity |
| Fine Chemicals | Used in the production of dyes, pigments, and other fine chemicals | Reacted with other chemical substances under controlled conditions to yield products with desired color or other functional properties |
| Research | Used as a reference standard or catalyst in laboratory studies | Employed directly or after appropriate preparation to evaluate performance or facilitate specific chemical reactions under experimental conditions |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase column with water-acetonitrile or methanol as the mobile phase, and UV detection (210–220 nm) to measure peak area of the main component. The content is calculated via external standard or internal standard method, suitable for quantitative analysis of main component purity. |
| Impurity Profile (Organic Impurities) | HPLC-UV / HPLC-MS | Gradient elution HPLC is used to separate potential impurities such as unreacted raw materials, by-products (e.g., isomers, hydrolysis products), and degradation substances. Coupled with mass spectrometry (MS) for structural identification, enabling both qualitative and quantitative analysis of impurities. |
| Water Content | Karl Fischer Titration | Employs an iodine-sulfur dioxide-pyridine-methanol system that reacts quantitatively with water. Water content is determined via electrochemical or volumetric titration, meeting pharmacopoeial standards (e.g., USP/EP) with ppm-level accuracy. |
| Residual Solvents | Gas Chromatography (GC-FID / GC-MS) | Headspace or direct injection using capillary columns to separate common organic solvents (e.g., methanol, ethanol, acetone, acetonitrile). FID detection is used for quantification, ensuring compliance with ICH Q3C guideline limits. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion, samples are analyzed using AAS to determine levels of heavy metals such as lead, cadmium, mercury, and arsenic; alternatively, inductively coupled plasma mass spectrometry (ICP-MS) enables simultaneous multi-element detection, meeting pharmaceutical standards (e.g., USP <232>). |
| pH Value (in aqueous solution) | Glass Electrode pH Meter | Sample is dissolved in purified water, and pH is directly measured using a calibrated pH meter, assessing acidity/basicity and detecting possible hydrolysis or acidic/basic impurities affecting stability. |
| Melting Point | Melting Point Apparatus Measurement | Measured using capillary tube method or automated melting point apparatus. The melting temperature range serves for compound identification and preliminary purity assessment—pure substances exhibit a narrow melting range, while impurities lower and broaden the melting point range. |
| Inorganic Anions (e.g., Chloride, Sulfate) | Ion Chromatography (IC) or Colorimetric Method | IC is used to separate and detect anions such as Cl⁻ and SO₄²⁻, or colorimetric methods (e.g., silver nitrate precipitation for chloride) are applied to control residual inorganic impurities, complying with pharmacopoeial general requirements. |
| Nitrogen Content (Elemental Analysis) | Elemental Analyzer (CHNS/O) | Sample is combusted at high temperature, followed by nitrogen content determination. Comparison with theoretical values helps verify molecular structure integrity, particularly useful for confirming synthetic intermediates. |
| Test Item | Specification |
|---|---|
| Appearance | Pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.420–1.430 |
| Relative Density (20°C/25°C) | 0.820–0.840 g/cm³ |
| Odor | Characteristic faint amine-like odor |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.