5-Acetyl-2-bromopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 139042-59-4 |
| Product name | 5-Acetyl-2-bromopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Acetyl-2-bromopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Acetyl-2-bromopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Acetyl-2-bromopyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for anti-inflammatory, antiviral, and anticancer drug development | Used as a key intermediate in multistep syntheses to construct complex molecular frameworks via coupling and substitution reactions |
| Agrochemicals | Synthesis of novel pesticide intermediates | Applied to build the core structures of pyridine-based insecticides or fungicides through nucleophilic substitution or metal-catalyzed coupling reactions |
| High-performance polymers | Synthesis of functional polymer monomers | Participates in polymerization reactions via its reactive bromine atom—for example, Diels–Alder reactions with dienes or palladium-catalyzed coupling polymerizations |
| Organic synthesis | General-purpose organic synthesis intermediate for constructing nitrogen-containing heterocycles | Leverages the high reactivity of its bromine atom in cross-coupling reactions such as Suzuki and Stille couplings, or undergoes nucleophilic addition via its acyl group |
Manufacturing Quality Control of 5-Acetyl-2-bromopyridine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities under natural or standard lighting conditions. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) with methanol/water or acetonitrile/water as the mobile phase. Detect at approximately 254 nm using a UV detector. Calculate purity of the main peak by external standard or area normalization method. |
| Assay | HPLC or Ultraviolet Spectrophotometry (UV) | HPLC: Quantify using a reference standard as described above; UV: Measure absorbance at the maximum absorption wavelength (typically around 280–300 nm) and calculate concentration based on the Lambert-Beer Law. |
| Moisture Content | Karl Fischer Titration | Use volumetric or coulometric Karl Fischer titrator to accurately determine total water content, including both free and bound water. |
| Residual Solvents | Gas Chromatography (GC) | Detect potentially residual organic solvents such as methanol, ethanol, acetone, dichloromethane, and ethyl acetate according to ICH guidelines, using headspace or direct solution injection. |
| Melting Point | Melting Point Apparatus | Determine initial and final melting temperatures using an automatic or manual melting point apparatus with a controlled temperature ramp; used to assess crystalline form and purity. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Measure residual levels of toxic elements such as lead, arsenic, cadmium, and mercury to comply with pharmacopoeial or safety standards (e.g., ICH Q3D). |
| Related Substances (Impurities) | HPLC | Separate the main component from degradation products or synthesis intermediates using gradient elution, detect and quantify impurity peaks to evaluate impurity profile and stability. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS), Fourier Transform Infrared Spectroscopy (FT-IR) | NMR (¹H, ¹³C) confirms molecular structure; MS identifies molecular ion and fragment ions; FT-IR analyzes characteristic functional group absorption peaks. |
Technical Specifications of 5-Acetyl-2-bromopyridine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 58–62°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Acetyl-2-bromopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Acetyl-2-bromopyridine
Packaging of 5-Acetyl-2-bromopyridine
Industrial 5-Acetyl-2-bromopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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