Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)- Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 139243-54-2 |
| Product name | Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)-
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)- Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)-
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthetic intermediate | Used to prepare γ-aminobutyric acid (GABA) analogs or chiral drug molecules via reactions including ester hydrolysis, amidation, and reductive amination |
| Organic synthesis | Chiral building block | Applied as a nitrogen-containing chiral small molecule in asymmetric synthesis to construct optically active drug or functional molecular scaffolds |
Manufacturing Quality Control of Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)-
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., R-3-aminobutanoic acid, methyl ester hydrolysis products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual methanol, dichloromethane, or ethyl acetate per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other toxic metals at trace levels using inductively coupled plasma mass spectrometry. |
| Chloride Content | Potentiometric Titration (AgNO₃) | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration from the hydrochloride salt counterion. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC-UV | Enantioseparation on a chiral stationary phase (e.g., Chiralpak AD-H) with UV detection to quantify R-enantiomer excess relative to S-impurity. |
| Residue on Ignition | Gravimetric Analysis | Incineration at 700–800 °C followed by weighing of non-volatile inorganic residue to assess inorganic ash content. |
| pH (1% aqueous solution) | pH Potentiometry | Measurement of hydrogen ion activity in a 1% w/v aqueous solution using calibrated pH electrode and buffer standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to determine D10, D50, D90 values per USP <429>. |
Technical Specifications of Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)-
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -21.0 to -19.0° (c=1, in H2O) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)-
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)-
Safety Information of Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)-
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)-
Industrial Butanoic acid, 3-aMino-, Methyl ester, hydrochloride, (R)- Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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