3-Bromo-4-cyanopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 13958-98-0 |
| Product name | 3-Bromo-4-cyanopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Bromo-4-cyanopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Bromo-4-cyanopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Bromo-4-cyanopyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for anticancer and antiviral drug development | Used to construct complex molecules containing cyano and bromopyridine moieties via nucleophilic substitution or coupling reactions |
| Agrochemicals | Synthesis of agrochemical intermediates for novel insecticides or fungicides | Applied as a heterocyclic scaffold in multistep syntheses to enhance biological activity and selectivity |
| Polymers & Materials | Functional monomer or crosslinker for specialty polymers | Introduced into polymer chains via Suzuki or Heck coupling reactions utilizing the bromo substituent |
| Fine Chemicals | Synthesis of dyes, photochromic materials, and optoelectronic functional molecules | Employed in metal-catalyzed coupling reactions to build conjugated systems, leveraging both cyano and bromo functional groups |
| Organic Synthesis | General-purpose organic synthesis intermediate for constructing multifunctional heterocyclic compounds | Commonly applied in palladium-catalyzed coupling reactions (e.g., Buchwald–Hartwig amination) and electrophilic substitution reactions |
Manufacturing Quality Control of 3-Bromo-4-cyanopyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., 3-bromo-pyridine, 4-cyanopyridine, bromination by-products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection (or mass spectrometry) to quantify residual solvents (e.g., DMF, dichloromethane, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous methanol/pyridine medium; measures trace water content precisely. |
| Heavy Metals | ICP-MS or ICP-OES | Quantitative multi-element analysis after acid digestion; detects toxic metals (e.g., Pb, Cd, Hg, As) at sub-ppb levels per ICH Q3D. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700–800 °C to oxidize organic matter; residue weight reflects inorganic ash content per USP <281>. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus; verifies identity and crystallinity per Ph. Eur. 2.2.14. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of chloride ions (e.g., from hydrochloride salt formation or synthesis residues) via suppressed conductivity detection or silver nitrate titration. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine D10, D50, D90 values relevant for handling and formulation. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 20 °C using sodium D-line; confirms chiral purity if applicable (though compound is achiral, used for batch consistency). |
Technical Specifications of 3-Bromo-4-cyanopyridine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78-82°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Bromo-4-cyanopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Bromo-4-cyanopyridine
Packaging of 3-Bromo-4-cyanopyridine
Industrial 3-Bromo-4-cyanopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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