China Factory Direct
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| CAS number | 139592-37-3 |
| Product name | (FMOC-CYS-OTBU)2, (DISULFIDE BOND) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Intermediate in the synthesis of peptide-based drugs | Used in solid-phase peptide synthesis as a protected form of cysteine (Cys), with the amino group protected by an Fmoc (9-fluorenylmethyloxycarbonyl) group and the thiol group protected by a tBuO (tert-butoxy) group |
| Organic Synthesis | Synthesis of cysteine-containing peptides or proteins | Serves as a building block in liquid-phase or solid-phase synthesis to construct peptide chains, providing specific functional groups for subsequent modification or coupling reactions |
| Chemical Reagents | Source of functional groups for molecular modification | Releases reactive functional groups upon deprotection (e.g., Fmoc and tBuO removal) for further chemical modification or bioconjugation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorbance at specified wavelength using reverse-phase C18 column and calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., diastereomers, hydrolysis products) via gradient elution and peak area comparison. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, DCM, MTBE) using flame ionization detection after headspace or direct injection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe) at sub-ppb levels using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-OES | Measures palladium catalyst residue via atomic emission from plasma-excited atoms at characteristic wavelengths. |
| Optical Rotation | [alpha]D Measurement | Determines specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Measures dry or wet dispersed particle size distribution based on angular scattering intensity of laser beam. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by weight loss after controlled heating under defined temperature and vacuum conditions. |
| Residual TFA | GC-FID | Quantifies trifluoroacetic acid by derivatization (e.g., with ethanol) followed by GC separation and FID detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| pH of Solution | Potentiometric Titration | Measures acidity/basicity of aqueous suspension via pH electrode calibrated against standard buffer solutions. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 75–79°C |
| Optical Rotation | -6.0 to -5.0° (c=1, DMF) |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.