Ethyl 2-bromo-5-fluorobenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 139911-28-7 |
| Product name | Ethyl 2-bromo-5-fluorobenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl 2-bromo-5-fluorobenzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 2-bromo-5-fluorobenzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 2-bromo-5-fluorobenzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used to synthesize fluorinated aromatic drug molecules, including anticancer, anti-inflammatory, and central nervous system-active compounds | Acts as an arylating reagent in transition metal-catalyzed reactions, such as Suzuki coupling and Buchwald–Hartwig amination |
| Agrochemical Intermediates | Serves as a precursor for synthesizing fluorinated benzoate-based insecticides or herbicides | Builds the target agrochemical molecular scaffold via hydrolysis, reduction, or nucleophilic substitution |
| Organic Synthesis | Functions as a versatile building block for introducing bromo and fluoro substituents into complex aromatic systems | Employs the bromo group for cross-coupling reactions and the fluoro group to modulate electronic properties and metabolic stability |
| Materials Science | Serves as a precursor for synthesizing fluorinated functional materials, such as liquid crystal monomers or optoelectronic materials | Incorporates into polymer backbones or side chains via transesterification, deprotection, or polymerization |
Manufacturing Quality Control of Ethyl 2-bromo-5-fluorobenzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., ethanol, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine-based reagent to determine trace water content by stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using plasma emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Acid Value | Acid-Base Titration | Neutralization of residual acidic impurities with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after controlled high-temperature ashing of sample in a platinum crucible. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light through a solution to assess chiral purity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie theory-based scattering pattern analysis. |
Technical Specifications of Ethyl 2-bromo-5-fluorobenzoate
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.545–1.555 |
| Relative Density (20°C/25°C) | 1.36–1.38 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl 2-bromo-5-fluorobenzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl 2-bromo-5-fluorobenzoate
Safety Information of Ethyl 2-bromo-5-fluorobenzoate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl 2-bromo-5-fluorobenzoate
Industrial Ethyl 2-bromo-5-fluorobenzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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