China Factory Direct
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| CAS number | 1400264-85-8 |
| Product name | tert-Butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate hydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic intermediate in the preparation of piperidine-containing drug molecules, such as antiviral agents and central nervous system (CNS) drugs | Applied in organic synthesis to construct the piperidine ring scaffold of target compounds via deprotection, alkylation, or acylation reactions |
| Pesticides | Potentially used in the synthesis of fluorinated heterocyclic pesticide intermediates with biological activity | Employed as a key building block in multistep syntheses to introduce fluorine atoms and the piperidine structure, thereby enhancing biological activity or metabolic stability |
| Fine Chemicals | Used as a precursor for fluorinated functional materials or ligands | Processed via functional group transformations (e.g., hydrolysis, reduction) to produce fluorinated fine chemicals with specific performance characteristics |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene) via gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pd, Ni, Fe) using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange. |
| Residual Palladium | ICP-OES | Measures palladium catalyst residue by atomic emission from high-temperature plasma. |
| Optical Rotation | Polarimetry | Determines specific optical rotation using sodium D-line light to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range of solid-to-liquid transition as indicator of crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine size distribution via light scattering pattern. |
| Bulk Density | USP <616> Tap Density Method | Determines mass per unit volume after controlled tapping to assess powder flow and handling properties. |
| Microbial Limits | Membrane Filtration + Culture | Detects aerobic microorganisms by filtration, membrane transfer to growth media, and colony enumeration. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 82.0–86.0 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic, non-offensive |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.