China Factory Direct
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| CAS number | 140148-70-5 |
| Product name | (3S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Chiral building block for synthesizing pharmaceutical intermediates | Introduces chiral centers via chiral catalysis or asymmetric synthesis |
| Chemical Feedstock | Intermediate for synthesizing other organic compounds | Converted through organic synthesis reactions such as esterification and amidation |
| Materials Science | Used in the preparation of functional or polymeric materials | Forms materials via polymerization or copolymerization with other monomers |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Separation of (S)- and (R)-enantiomers on a chiral stationary phase, with UV detection and calculation of ee from peak area ratio. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., THF, EtOAc, MeOH) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, with detection at sub-pptr levels. |
| Residual BOC Reagent (Di-tert-butyl dicarbonate) | GC-MS | Detection and quantification via gas chromatography coupled with mass spectrometry using characteristic fragment ions. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Identification and quantification of process-related impurities and degradation products using stability-indicating HPLC method. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration at 600–750 °C. |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation using a polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral identity and batch consistency. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values per USP <429>. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (GC-MS) |
| Optical Rotation | +14.0° to +16.0° (c=1, in methanol) |
| Melting Point | 78°C to 82°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.