7-((2-(triMethylsilyl)ethoxy)Methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1404364-72-2 |
| Product name | 7-((2-(triMethylsilyl)ethoxy)Methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1404364-72-2
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1404364-72-2 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1404364-72-2
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical Intermediates | Used as a key intermediate in the synthesis of targeted antitumor agents or other kinase inhibitors, enabling coupling reactions to construct the active molecular scaffold |
| Organic Synthesis | Synthesis of Pyrrolopyrimidine Derivatives | Applied as a reaction intermediate in Suzuki or Heck couplings to introduce iodine- and chlorine-containing functional groups for subsequent structural modification |
| Fine Chemicals | Specialty Chemicals Production | Employed in the preparation of biologically active nitrogen-containing heterocyclic compounds, serving as a structural building block for novel agrochemical or pharmaceutical active ingredients |
| Materials Science | Functional Material Precursor | Utilized in the synthesis of optoelectronic or organic semiconductor materials, providing modifiable functional groups to tailor material properties |
Manufacturing Quality Control of 1404364-72-2
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at specified wavelength based on peak area response against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection; identification and reporting per ICH Q3B thresholds. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., toluene, THF, DMF) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residual Catalyst (Pd) | ICP-OES | Measures palladium residue post-catalytic synthesis using inductively coupled plasma optical emission spectrometry after microwave-assisted digestion. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus under controlled heating rate. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under specified temperature, vacuum, and time conditions. |
| Optical Rotation | Polarimetry | Quantifies specific rotation using sodium D-line light source and standardized cell path length to assess chiral purity. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in suspension using Mie scattering theory and calibrated laser diffraction instrument. |
| pH of Aqueous Slurry | Potentiometric pH Measurement | Determines pH of saturated aqueous slurry using calibrated glass electrode and pH meter per USP <791>. |
Technical Specifications of 1404364-72-2
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1404364-72-2
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1404364-72-2
Packaging of 1404364-72-2
Industrial 1404364-72-2 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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