China Factory Direct
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| CAS number | 1404373-75-6 |
| Product name | 1-(3-Oxetanyl)piperazine trifluoroacetate (1:2) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Drug synthesis intermediate | Used as a piperazine derivative to construct drug molecule scaffolds containing both piperazine and oxetane rings. |
| Pharmaceutical Chemicals | Preparation of specialty salt forms | Applied as the bis(trifluoroacetate) salt to enhance water solubility and crystallinity of the intermediate, facilitating charging and purification in subsequent reactions. |
| Research & Development | Targeted drug research | Employed in the early-stage design and synthesis of compounds with specific biological activity, such as kinase inhibitors or receptor antagonists. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/HRMS | Separation and identification of impurities via gradient HPLC coupled with high-resolution mass spectrometry for structural elucidation and semi-quantitation. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., acetonitrile, methanol, DCM) based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS | Quantification of elemental impurities (e.g., Pb, Cd, As, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppt sensitivity. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anion using suppressed conductivity detection following aqueous elution on an anion-exchange column. |
| Residual Catalyst (Pd) | ICP-OES | Determination of palladium content after microwave-assisted nitric/hydrochloric acid digestion, measured by inductively coupled plasma optical emission spectroscopy. |
| Optical Rotation | [α]D | Measurement of specific optical rotation using a digital polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in aqueous suspension to assess acidity/basicity consistent with salt hydrolysis behavior. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser diffraction to determine D10, D50, D90 values, relevant for dissolution and handling properties. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.