(R)-N-Boc-3-aminomethylpiperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 140645-23-4 |
| Product name | (R)-N-Boc-3-aminomethylpiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-N-Boc-3-aminomethylpiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-N-Boc-3-aminomethylpiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-N-Boc-3-aminomethylpiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of drug molecules, such as NK1 receptor antagonists (e.g., aprepitant) and other piperidine-containing active pharmaceutical ingredients (APIs) | Employed in multistep organic synthesis to construct target molecules via deprotection (e.g., Boc removal), acylation, alkylation, and other transformations; commonly applied in asymmetric synthesis or chiral drug construction steps |
| Pesticides | Potentially used in synthesizing biologically active nitrogen-containing heterocyclic pesticide intermediates | Applied as a building block in heterocycle synthesis for developing novel insecticides or fungicides |
| Research | Used in synthesizing chiral ligands or catalysts, and in structure–activity relationship (SAR) studies within medicinal chemistry | Utilized at laboratory scale for structural modification, derivatization, and high-throughput screening |
Manufacturing Quality Control of (R)-N-Boc-3-aminomethylpiperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-220 nm, comparing peak area to reference standard. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separation on chiral stationary phase and UV detection. |
| Water Content | Karl Fischer Titration | Determines water via coulometric or volumetric titration with iodine-based reagent reacting stoichiometrically with water. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and detects chloride ions using suppressed conductivity detection after anion exchange. |
| Sulfate Impurity | Ion Chromatography | Separates and detects sulfate ions using suppressed conductivity detection after anion exchange. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection. |
| Residual Boc Reagent | HPLC-UV | Monitors di-tert-butyl dicarbonate and tert-butanol by HPLC-UV under specified conditions. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid sample against established visual standards. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus. |
| Specific Optical Rotation | Polarimetry | Measures angle of rotation of plane-polarized light in solution to confirm chiral identity and enantiomeric integrity. |
Technical Specifications of (R)-N-Boc-3-aminomethylpiperidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | +17.5 to +19.5 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-N-Boc-3-aminomethylpiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-N-Boc-3-aminomethylpiperidine
Safety Information of (R)-N-Boc-3-aminomethylpiperidine
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-N-Boc-3-aminomethylpiperidine
Industrial (R)-N-Boc-3-aminomethylpiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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